Cefixime Impurity 1 CAS 246035-38-1
| CAS No. | 246035-38-1 |
| Molecular Formula | C15H12N4O4S3 |
| Molecular Weight | 408.48 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Structurally, Cefixime Impurity 1 (C15H12N4O4S3) contains a flavonoid core, an amide group, a sulfone group, a hydroxyl group, an ether linkage. The molecule exhibits a degree of unsaturation (DBE) of 12.0, corresponding to approximately 12 ring(s) or double-bond equivalent(s). With a molecular weight of 408.48 g/mol, it falls into the moderately-high-molecular-weight range. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
CATO supplies Cefixime Impurity 1 (CAS 246035-38-1), a pharmacopoeial impurity reference standard (molecular formula C15H12N4O4S3, MW 408.48 g/mol) used for the identification and quantification of trace impurities in APIs.
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C15H12N4O4S3 |
| Molecular Weight | 408.48 g/mol |
| Purity | >80% |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 12.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Nitrogen Atoms | 4 |
| Sulfur Atoms | 3 |
Related Cefixime Standards
- Cefixime Impurity 82 (CAS CATO-C4X-113982)
- Cefixime Impurity 86 (CAS CATO-C4X-113986)
- Cefixime Impurity 10 (CAS CATO-C4X-113910)
- Cefixime Impurity 13 (CAS CATO-C4X-113913)
- Cefixime EP Impurity B (CAS 1335475-19-8)
- Cefixime EP Impurity B (CAS CATO-C4X-113992)
- Cefixime Impurity 93 (CAS CATO-C4X-113993)
- Cefixime Impurity 94 (CAS CATO-C4X-113994)
Recommended Standards
- 6-(Adamantan-1-yl)-2-((3-oxobutan-2-yl)thio)-4-(trifluoromethyl)nicotinonitrile (CAS 625376-60-5)
- 2-(Methylthio)-4-((3-(trifluoromethyl)phenyl)thio)benzo[4,5]thieno[3,2-d]pyrimidine (CAS 477872-84-7)
- 2,2-Bis(4-methoxyphenyl)-1,2-diphenylethanone (CAS 103281-33-0)
- 1-(4-Methylbenzenesulfonyl)-3-[5-(pyrazin-2-ylsulfanyl)-1,3,4-thiadiazol-2-yl]urea (CAS 866042-93-5)
- Citicoline Impurity 6 (CAS 52448-10-9)
- Benzhexol Impurity 6 (CAS CATO-C4X-18576)
- N-Nitroso-Moxifloxacin impurity 173 (CAS CATO-C4X-1074173)
- N-(3-Aminopropyl)imidodicarbonimidic diamide (CAS 133029-31-9)
- 2-(Cyclopropylmethoxy)-4,6-dimethylbenzonitrile (CAS 1710853-40-9)
- 2,2-(Methylimino)bis(N-ethyl-N,N-dimethylethanaminium) dibromide (CAS 306-53-6)
- 4-(4-Methoxybenzylidene)-3-phenylisoxazol-5(4H)-one (CAS 50779-89-0)
- 3-Methyl-4-pyridinethiol (CAS 10351-13-0)
- Esomeprazole Impurity 129 (CAS CATO-C4X-1112129)
- Liraglutide Impurity 16 TFA Salt (CAS CATO-C4X-199216)
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