5-Hydroxy-2-methylpyrimidin-4(1H)-one CAS 24614-14-0

Purity 97%+In StockPharmaceutical Standards
CAS No.24614-14-0
Molecular FormulaC11H11FO
Molecular Weight178.20 g/mol
CategoryPharmaceutical Standards / API Standards
AvailabilityIn Stock

Chemical Structure

5-Hydroxy-2-methylpyrimidin-4(1H)-one CAS 24614-14-0 chemical structure

Description

The occurrence of 5-Hydroxy-2-methylpyrimidin-4(1H)-one is closely related to a hydroxyl group, an ether linkage, fluorine substitution, an aromatic ring system in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.

CATO supplies 5-Hydroxy-2-methylpyrimidin-4(1H)-one (CAS 24614-14-0), a certified reference material (molecular formula C11H11FO, MW 178.20 g/mol) for analytical method development and quality control.

Owing to a hydroxyl group, an ether linkage, fluorine substitution, an aromatic ring system, 5-Hydroxy-2-methylpyrimidin-4(1H)-one is typically off-white to pale yellow low-melting solid. Its solid-state physicochemical attributes — including a molecular weight of 178.20 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

As a certified reference material (CRM), 5-Hydroxy-2-methylpyrimidin-4(1H)-one meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.

Physical & Chemical Properties

Molecular FormulaC11H11FO
Molecular Weight178.20 g/mol
Purity97%+
StorageStore at 2-8°C, protect from light, keep tightly closed to prevent evaporation
Solubility (reference)Soluble in chloroform, dichloromethane, ethyl acetate, DMSO
StabilityMay oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light
Degree of Unsaturation (DBE)6.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
CAS Registry Year (est.)1964
Halogen ContentF-containing

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