5,6,7,8-Tetrahydro[1,6]naphthyridine dihydrochloride CAS 348623-30-3
| CAS No. | 348623-30-3 |
| Molecular Formula | C8H10N2 |
| Molecular Weight | N/A |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
5,6,7,8-Tetrahydro[1,6]naphthyridine dihydrochloride (CAS 348623-30-3) is a high-purity analytical reference standard with the molecular formula C8H10N2HCl and a molecular weight of 170.64 g/mol.
5,6,7,8-Tetrahydro[1,6]naphthyridine dihydrochloride (C8H10N2HCl) contains a nitrogen-containing heterocyclic scaffold, a nitrile group, chlorine substitution. Halogen substitution raises its density and boiling point; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), 5,6,7,8-Tetrahydro[1,6]naphthyridine dihydrochloride meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C8H10N2 2*HCl |
| Molecular Weight | 170.64 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 4.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 2 |
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Recommended Standards
- 2-Fluoro-5-(thiophen-3-yl)pyridine (CAS 837376-41-7)
- 2-(3-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)-2,3-dihydro-1H-naphtho[1,8-de][1,3,2]diazaborinine (CAS 950511-17-8)
- 4-Cyano-3,5-dimethylbenzene-1-sulfonyl chloride (CAS 1807275-52-0)
- Empagliflozin Impurity 96 (CAS 106941-19-9)
- Cholic Acid Impurity 31 (CAS CATO-C4X-116031)
- 2-Bromo-N-(cyanomethyl)benzamide (CAS 143183-01-1)
- 1-Chloro-3-ethynyl-2-methoxybenzene (CAS 2228704-35-4)
- piperidine-4-sulfonamide (CAS 878388-34-2)
- 2-(3-Amino-5-chloropyridin-2-yl)acetic acid (CAS 886373-86-0)
- Semaglutide impurity 65 (CAS CATO-C4X-222665)
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