6-Bromobenzo[b]thiophene 1,1-dioxide CAS 246177-22-0
| CAS No. | 246177-22-0 |
| Molecular Formula | C8H5BrO2S |
| Molecular Weight | 245.09 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
6-Bromobenzo[b]thiophene 1,1-dioxide (CAS 246177-22-0), molecular formula C8H5BrO2S and molecular weight 245.09 g/mol, is a CATO reference standard with documented purity and traceability.
The molecular framework of 6-Bromobenzo[b]thiophene 1,1-dioxide (C8H5BrO2S) is characterized by a sulfone group, a carboxylic acid group, a hydroxyl group, an ether linkage, bromine substitution, an aromatic ring system. In reversed-phase chromatography, its retention is governed primarily by the polarity and ionization state of its functional groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
CATO manufactures 6-Bromobenzo[b]thiophene 1,1-dioxide under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C8H5BrO2S |
| Molecular Weight | 245.09 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 6.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | Br-containing |
| Sulfur Atoms | 1 |
Related Bromobenzo Standards
- 2-Bromobenzo[b]thiophene 1,1-dioxide (CAS 5350-05-0)
- 4-Bromobenzo[b]thiophene 1,1-dioxide (CAS 5118-14-9)
- 5-Bromobenzo[1,3]dioxole-4-carboxylic acid (CAS 72744-56-0)
- 6-Bromobenzo[d][1,3]dioxole-4-carboxylic acid (CAS 72744-57-1)
- 6-Bromobenzo[d][1,3]dioxole-5-carboxylic Acid (CAS 60546-62-5)
- (6-Bromobenzo[d][1,3]dioxol-4-yl)boronic acid (CAS 1150114-39-8)
- 5-Bromobenzo[1,3]dioxole-4-boronic acid (CAS 1451392-88-3)
- (2-Bromobenzo[d]thiazol-6-yl)methanol (CAS 214337-28-7)
Recommended Standards
- 6-Bromo-8-fluoro-2,2-dimethyl-2,3-dihydroimidazo[1,2-a]pyridine (CAS 2653201-96-6)
- 7-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-[1,2,4]triazolo[4,3-a]pyridine (CAS 2260710-34-5)
- 6-Amino-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)nicotinonitrile (CAS 2096334-03-9)
- 7-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-benzo[d][1,2,3]triazole (CAS 2379560-98-0)
- N-(2-(2-(2-(4-Chlorophenyl)acetyl)hydrazine-1-carbonyl)phenyl)thiophene-2-carboxamide (CAS 1090837-09-4)
- N-(4-Hydroxyphenyl)cinnamamide (CAS 3579-85-9)
- Propan-2-yl (2s)-pyrrolidine-2-carboxylate (CAS 61114-37-2)
- 5-Oxo-5-(phenylamino)pentanoic acid (CAS 5414-99-3)
- n-(Tert-butyl)-n-(2,2,2-trifluoroacetyl)glycine (CAS 1536895-50-7)
- Ethyl 7-hydroxytetrazolo[1,5-a]pyrimidine-6-carboxylate (CAS 1778637-73-2)
- 1-[3,5-Bis(trifluoromethyl)phenyl]cyclopropanamine (CAS 1266148-15-5)
- VX-984 (CAS 1562396-65-9)
- Methyl 1,3-dimethyl-2-oxo-2,3-dihydro-1H-benzo[d]imidazole-5-carboxylate (CAS 222424-21-7)
- D-[Ser]8-Semaglutide (CAS CATO-CPTD788632)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com