5-Bromobenzo[1,3]dioxole-4-boronic acid CAS 1451392-88-3
| CAS No. | 1451392-88-3 |
| Molecular Formula | C7H6BBrO4 |
| Molecular Weight | 244.84 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
5-Bromobenzo[1,3]dioxole-4-boronic acid (CAS 1451392-88-3) is a high-purity analytical reference standard with the molecular formula C7H6BBrO4 and a molecular weight of 244.84 g/mol.
The molecular framework of 5-Bromobenzo[1,3]dioxole-4-boronic acid (C7H6BBrO4) is characterized by a carboxylic acid group, a hydroxyl group, an ether linkage, bromine substitution, an aromatic ring system. In reversed-phase chromatography, its retention is governed primarily by the polarity and ionization state of its functional groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C7H6BBrO4 |
| Molecular Weight | 244.84 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO, water |
| Stability | May oxidize slowly on prolonged air exposure; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 4.5 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1992 |
| Halogen Content | Br-containing |
Related Bromobenzo Standards
- (6-Bromobenzo[d][1,3]dioxol-4-yl)boronic acid (CAS 1150114-39-8)
- 5-Bromobenzo[1,3]dioxole-4-carboxylic acid (CAS 72744-56-0)
- 6-Bromobenzo[d][1,3]dioxole-4-carboxylic acid (CAS 72744-57-1)
- 6-Bromobenzo[d][1,3]dioxole-5-carboxylic Acid (CAS 60546-62-5)
- 2-Bromobenzo[b]thiophene 1,1-dioxide (CAS 5350-05-0)
- 4-Bromobenzo[b]thiophene 1,1-dioxide (CAS 5118-14-9)
- 6-Bromobenzo[b]thiophene 1,1-dioxide (CAS 246177-22-0)
- (2-Bromobenzo[d]thiazol-6-yl)methanol (CAS 214337-28-7)
Recommended Standards
- 3-Borono-4-bromobenzoic acid (CAS 1448312-00-2)
- 4-Bromo-3-carboxyphenylboronic acid (CAS 1451393-32-0)
- 3-Borono-5-bromobenzoic acid (CAS 913835-73-1)
- 836-42-0 A840619 [1-amino-2-(1H-indol-3-yl)ethyl]phosphonic acid [1-azanyl-2-(1H-indol-3-yl)ethyl]phosphonic acid (CAS 836-42-0)
- Dimethyl 2-(thiophen-2-ylmethyl)malonate (CAS 122308-25-2)
- Ethyl 2-iodo-5-nitrobenzoate (CAS 835916-53-5)
- Ethyl 5-chlorobenzofuran-3-carboxylate (CAS 899795-65-4)
- 2-Methyl-1-pentylindole (CAS 42951-36-0)
- 3-Fluoro-2-(propan-2-yloxy)benzoic acid (CAS 1248479-48-2)
- Ethyl 3-methyl-2-oxo-2,3-dihydro-1H-benzo[d]imidazole-4-carboxylate (CAS 1506387-29-6)
- Tolvaptan Impurity 24 (CAS 150683-27-5)
- 4-(5-Azaspiro[2.4]heptan-5-yl)benzoic acid (CAS 2021743-28-0)
- 2-(4-Chloro-6-(difluoromethyl)-3-methoxypyridin-2-yl)acetic acid (CAS 1804665-09-5)
- MOTS-c Peptide (CAS 1627580-64-6)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com