(3-Chloro-2-fluoro-6-methoxyphenyl)boronic acid CAS 2468229-20-9
| CAS No. | 2468229-20-9 |
| Molecular Formula | C7H7BClFO3 |
| Molecular Weight | 204.39 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
(3-Chloro-2-fluoro-6-methoxyphenyl)boronic acid (CAS 2468229-20-9) is a high-purity analytical reference standard with the molecular formula C7H7BClFO3 and a molecular weight of 204.39 g/mol.
Owing to a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution, (3-Chloro-2-fluoro-6-methoxyphenyl)boronic acid is typically white to off-white crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 204.39 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), (3-Chloro-2-fluoro-6-methoxyphenyl)boronic acid meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C7H7BClFO3 |
| Molecular Weight | 204.39 g/mol |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO, water |
| Stability | May oxidize slowly on prolonged air exposure; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 3.5 |
| UV Absorption | UV-absorbing |
| CAS Registry Year (est.) | 2000 |
| Halogen Content | F/Cl-containing |
Related Chloro Standards
- (2-Chloro-6-fluoro-3-methoxyphenyl)boronic acid (CAS 1072945-77-7)
- (5-Chloro-2-fluoro-4-methoxyphenyl)boronic acid (CAS 1072952-18-1)
- 2-Chloro-4-fluoro-5-methoxyphenylboronic Acid (CAS 1256355-46-0)
- 3-Chloro-4-fluoro-5-methoxyphenylboronic acid (CAS 1379466-82-6)
- (4-Chloro-5-fluoro-2-methoxyphenyl)boronic acid (CAS 1443379-11-0)
- (3-Chloro-5-fluoro-4-methoxyphenyl)boronic acid (CAS 1451392-04-3)
- 4-Chloro-2-fluoro-3-hydroxymethylphenylboronic acid (CAS 1451393-58-0)
- (4-Chloro-2-fluoro-5-methoxyphenyl)boronic acid (CAS 153122-60-2)
Recommended Standards
- (3-Chloro-2-fluoro-4-methoxyphenyl)boronic acid (CAS 2096454-16-7)
- (5-Chloro-4-fluoro-2-methoxyphenyl)boronic acid (CAS 949892-09-5)
- (2-Chloro-3-fluoro-4-methoxyphenyl)boronic acid (CAS 2282635-50-9)
- (6-Chloro-2-fluoro-3-methoxyphenyl)boronic acid (CAS 867333-04-8)
- (2-Ethylpyridin-4-yl)methanamine (CAS 645418-40-2)
- (6-(Cyclopropylamino)pyridin-2-yl)boronic acid (CAS 1309982-29-3)
- n-(2-Methoxyethyl)-4,4-dimethylcyclohexan-1-amine (CAS 1342746-63-7)
- 4-Amino-2-(pyrrolidin-1-yl)pyrimidine-5-carbonitrile (CAS 55441-53-7)
- Nikethamide Impurity 8 (CAS 530-40-5)
- 2-Amino-4-(2-(benzyloxy)phenyl)-5-oxo-5,6,7,8-tetrahydro-4H-chromene-3-carbonitrile (CAS 337499-03-3)
- N-(2,4-Difluorophenyl)-6-nitro-4-quinazolinamine (CAS 184360-66-5)
- (S)-tert-Butyl 2-methylpiperidine-1-carboxylate (CAS 183903-99-3)
- 3-Phenyloxindole, 97% (CAS 3456-79-9)
- Semaglutide impurity 51 (CAS CATO-C4X-222651)
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