B-(4-Chloro-2-fluoro-6-hydroxyphenyl)boronic acid CAS 2470930-46-0
| CAS No. | 2470930-46-0 |
| Molecular Formula | C6H5BClFO3 |
| Molecular Weight | 190.36 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
CATO supplies B-(4-Chloro-2-fluoro-6-hydroxyphenyl)boronic acid (CAS 2470930-46-0), a certified reference material (molecular formula C6H5BClFO3, MW 190.36 g/mol) for analytical method development and quality control.
Owing to a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution, B-(4-Chloro-2-fluoro-6-hydroxyphenyl)boronic acid is typically white to off-white crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 190.36 g/mol — guide the selection of appropriate sample preparation and analytical techniques. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C6H5BClFO3 |
| Molecular Weight | 190.36 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO, water |
| Stability | May oxidize slowly on prolonged air exposure; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 3.5 |
| UV Absorption | UV-absorbing |
| CAS Registry Year (est.) | 2000 |
| Halogen Content | F/Cl-containing |
Related B Standards
- (3-Chloro-5-fluoro-4-hydroxyphenyl)boronic acid (CAS 1003298-72-3)
- 3-Chloro-4-fluoro-5-hydroxyphenylboronic acid (CAS 1379466-81-5)
- (4-Chloro-2-fluoro-3-hydroxyphenyl)boronic acid (CAS 1451393-13-7)
- (3-Chloro-2-fluoro-6-hydroxyphenyl)boronic acid (CAS 2573799-47-8)
- (3-Chloro-6-fluoro-2-hydroxyphenyl)boronic acid (CAS 2134622-97-0)
- 2-Chloro-6-fluoro-3-hydroxyphenylboronic Acid (CAS 957121-07-2)
- 2-Chloro-6-fluoro-5-hydroxyphenylboronic acid (CAS 958646-67-8)
- 3-Chloro-5-fluoro-2-hydroxyphenylboronic acid (CAS 2121515-30-6)
Recommended Standards
- 6-((Trimethylsilyl)oxy)hexan-1-ol (CAS 5665-79-2)
- Trimethyl(2-phenylallyl)silane (CAS 77130-15-5)
- 5-Chloro-2-fluoro-4-hydroxyphenylboronic acid (CAS 2121512-43-2)
- Trimethyl(4-vinylbenzyl)silane (CAS 64268-25-3)
- Ethyl 2-(2-{[3-cyano-6-methyl-4-(thiophen-2-yl)-5,6,7,8-tetrahydro-1,6-naphthyridin-2-yl]sulfanyl}acetamido)-4,5,6,7-tetrahydro-1-benzothiophene-3-carboxylate (CAS 445383-33-5)
- 1-(2,2-diethoxyethoxy)-3-(trifluoromethyl)benzene (CAS 63212-88-4)
- 5'-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)spiro[cyclopropane-1,1'-isoindolin]-3'-one (CAS 1626335-64-5)
- N-(9,9-dimethyl-9H-fluoren-4-yl)-9,9-dimethyl-9H-fluoren-2-amine (CAS 1644054-07-8)
- 4-(Pyrrolidin-1-yl)cyclohexane-1-carboxylic acid (CAS 1368871-80-0)
- L-altrose (CAS 1949-88-8)
- 1-(Bromomethyl)-1-ethoxy-4-methylcyclohexane (CAS 1250765-74-2)
- 2-(3-Methoxyphenyl)ethanohydrazide (CAS 34624-38-9)
- 5-[[(2R)-2-aminobutyl]amino]-2-(2,6-dioxo-3-piperidyl)isoindoline-1,3-dione (CAS 2728765-69-1)
- Semaglutide impurity 81 (CAS CATO-C4X-222681)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com