5,7-difluoro-2,3-dihydro-1H-indol-2-one CAS 247564-59-6
| CAS No. | 247564-59-6 |
| Molecular Formula | C8H11F2NO |
| Molecular Weight | 175.18 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
5,7-difluoro-2,3-dihydro-1H-indol-2-one (CAS 247564-59-6), molecular formula C8H11F2NO and molecular weight 175.18 g/mol, is a CATO reference standard with documented purity and traceability.
Owing to an amide group, a hydroxyl group, an ether linkage, fluorine substitution, 5,7-difluoro-2,3-dihydro-1H-indol-2-one is typically white to pale yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 175.18 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C8H11F2NO |
| Molecular Weight | 175.18 g/mol |
| Appearance | White to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 3.0 |
| UV Absorption | UV-absorbing |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 1 |
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Recommended Standards
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- Aflatoxin B2 (CAS 7220-81-7)
- 1-(2,4-Dichlorophenyl)-3-(dimethylamino)-2-methylprop-2-en-1-one (CAS 300709-89-1)
- 2-Fluoro-3-methyl-5-(pyridin-3-yl)pyridine (CAS 1214339-11-3)
- Methyl 5-Formyl-2-hydroxybenzoate (CAS 41489-76-3)
- tert-Butyl 1-[(tetrahydro-2H-pyran-4-yl)methyl]piperidin-4-ylcarbamate (CAS 1286275-85-1)
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