1-(Chloromethyl)-4-fluoro-2-(trifluoromethyl)benzene CAS 248262-29-5
| CAS No. | 248262-29-5 |
| Molecular Formula | C8H5ClF4 |
| Molecular Weight | 212.57 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO supplies 1-(Chloromethyl)-4-fluoro-2-(trifluoromethyl)benzene (CAS 248262-29-5), a certified reference material (molecular formula C8H5ClF4, MW 212.57 g/mol) for analytical method development and quality control.
Owing to fluorine/chlorine substitution, an aromatic ring system, 1-(Chloromethyl)-4-fluoro-2-(trifluoromethyl)benzene is typically off-white to pale yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 212.57 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
CATO manufactures 1-(Chloromethyl)-4-fluoro-2-(trifluoromethyl)benzene under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C8H5ClF4 |
| Molecular Weight | 212.57 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at room temperature, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO |
| Stability | May oxidize slowly on prolonged air exposure |
| Degree of Unsaturation (DBE) | 4.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | F/Cl-containing |
Related Chloromethyl Standards
- 2-(Chloromethyl)-1-fluoro-3-(trifluoromethyl)benzene (CAS 1001096-10-1)
- 1-(Chloromethyl)-2,3,5,6-tetrafluoro-4-methylbenzene (CAS 60903-84-6)
- 1-(Chloromethyl)-3-fluoro-5-(trifluoromethyl)benzene (CAS 634151-25-0)
- 2-(Chloromethyl)-1-fluoro-4-(trifluoromethyl)benzene (CAS 883543-26-8)
- 2-(Chloromethyl)-4-fluoro-1-(trifluoromethyl)benzene (CAS 832113-94-7)
- 2-(Chloromethyl)-6-(trifluoromethyl)pyrimidin-4-ol (CAS 1240596-45-5)
- 2-(Chloromethyl)-5-nitro-1,3-benzoxazole (CAS 119198-10-6)
- 2-(Chloromethyl)-4-nitrobenzo[d]oxazole (CAS 143708-26-3)
Recommended Standards
- 1-Chloro-2-fluoro-3-methyl-4-(trifluoromethyl)benzene (CAS 1805112-84-8)
- 3-Fluoro-4-(trifluoromethyl)benzyl chloride (CAS 444915-54-2)
- 1-(2-Chloro-1,1-difluoroethyl)-2,4-difluorobenzene (CAS 1204296-01-4)
- 4-Fluoro-3-trifluoromethylbenzyl chloride (CAS 67515-62-2)
- Boc-Ile-OH (CAS 13139-16-7)
- 3-(Dimethylamino)-1-(3-nitrophenyl)propan-1-one hydrochloride (CAS 63352-94-3)
- N-(2-(6-formyl-7-methoxybenzo[d][1,3]dioxol-5-yl)ethyl)-N-methylbenzamide (CAS 111441-33-9)
- 1-(1,2,4-oxadiazol-3-yl)ethan-1-ol (CAS 1594533-43-3)
- Ethyl[2-(2-Fluorophenyl)ethyl]amine (CAS 732245-62-4)
- Methyl 2-(3-Fluoro-4-nitrophenyl)acetate (CAS 169339-41-7)
- Pyrazolo[1,5-a]pyridin-3-amine dihydrochloride (CAS 1438424-29-3)
- 4,4,5,5-Tetramethyl-2-(3-methylbut-1-en-2-yl)-1,3,2-dioxaborolane (CAS 177949-93-8)
- 8-Methoxy-1,2,3,4-tetrahydroquinoline-3-carboxylic acid (CAS 1368244-09-0)
- Semaglutide impurity 289 (CAS CATO-C4X-2226289)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com