Metoclopramide Impurity 84 CAS 2486-67-1
| CAS No. | 2486-67-1 |
| Molecular Formula | C13H17NO4 |
| Molecular Weight | 251.28 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
As a certified reference material (CRM), Metoclopramide Impurity 84 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Metoclopramide Impurity 84 (CAS 2486-67-1) is a certified pharmaceutical impurity reference standard with the molecular formula C13H17NO4 and a molecular weight of 251.28 g/mol.
The molecular framework of Metoclopramide Impurity 84 (C13H17NO4) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
Physical & Chemical Properties
| Molecular Formula | C13H17NO4 |
| Molecular Weight | 251.28 g/mol |
| Appearance | Off-white to pale yellow crystalline powder |
| Purity | >95% |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 6.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1957 |
| Nitrogen Atoms | 1 |
Related Metoclopramide Standards
- Metoclopramide Impurity 86 (CAS CATO-C4X-141586)
- Metoclopramide Impurity 33 (CAS 62726-02-7)
- Metoclopramide Impurity 125 (CAS 476615-04-0)
- Metoclopramide impurity 78 (CAS CATO-C4X-141578)
- Metoclopramide Impurity 17 (CAS CATO-C4X-141517)
- Metoclopramide EP Impurity B (CAS 4093-31-6)
- Metoclopramide Impurity 24 (CAS CATO-C4X-141524)
- Metoclopramide (CAS CATO-C4X-141557)
Recommended Standards
- Enalaprilat EP Impurity A (S,S-Isomer) (CAS 84023-58-5)
- Voglibose Impurity 26 (CAS CATO-C4X-178026)
- Enalapril Maleate Impurity 28 (CAS CATO-C4X-133428)
- Neostigmine Impurity 13 (CAS 4939-59-7)
- Milrinone Impurity 35 (CAS 52600-51-8)
- Butylphthalide Impurity 46 (CAS 26311-42-2)
- Amlodipine Impurity N18 (CAS 72569-97-2)
- 3-(5-(2-Chlorophenyl)furan-2-yl)-N-(m-tolyl)acrylamide (CAS 853348-23-9)
- 5-[(4-nitro-1h-pyrazol-1-yl)methyl]furan-2-carbaldehyde (CAS 512809-43-7)
- 1-Isobutyl-7-methoxy-2,3,4,9-tetrahydro-1H-pyrido[3,4-b]indole (CAS 175975-76-5)
- 2-Chloro-N,N-diethylquinazolin-4-amine (CAS 35691-09-9)
- 2-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)-3,6-dichlorobenzoic acid (CAS 1691057-24-5)
- (2R)-2-ethynylazetidine;hydrochloride (CAS 2306254-11-3)
- Semaglutide impurity 60 (CAS CATO-C4X-222660)
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