Elagolix Impurity 22 CAS 2486454-63-9
| CAS No. | 2486454-63-9 |
| Molecular Formula | C32H29F5N3NaO6 |
| Molecular Weight | 669.57 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including Elagolix Impurity 22.
CATO supplies Elagolix Impurity 22 (CAS 2486454-63-9), a pharmacopoeial impurity reference standard (molecular formula C32H29F5N3NaO6, MW 669.57 g/mol) used for the identification and quantification of trace impurities in APIs.
Structurally, Elagolix Impurity 22 (C32H29F5N3NaO6) contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine substitution. The molecule exhibits a degree of unsaturation (DBE) of 17.5, corresponding to approximately 17 ring(s) or double-bond equivalent(s). With a molecular weight of 669.57 g/mol, it falls into the high-molecular-weight range. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C32H29F5N3NaO6 |
| Molecular Weight | 669.57 g/mol |
| Purity | >95% |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 17.5 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2000 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 3 |
Related Elagolix Standards
- Elagolix Impurity 23 (CAS CATO-C4X-206823)
- Elagolix Impurity 46 (CAS CATO-C4X-206846)
- Elagolix Impurity 86 (CAS CATO-C4X-206886)
- Elagolix Impurity 84 (CAS CATO-C4X-206884)
- Elagolix Impurity 58 (CAS CATO-C4X-206858)
- Elagolix Impurity 49 (CAS CATO-C4X-206849)
- Elagolix Impurity 52 (CAS 2756307-49-8)
- Elagolix Impurity 64 (CAS CATO-C4X-206864)
Recommended Standards
- N,N',N''-((3S,7S,11S)-2,6,10-Trioxo-1,5,9-trioxacyclododecane-3,7,11-triyl)tris(2,3-dihydroxybenzamide) (CAS 28384-96-5)
- Becatecarin (CAS 119673-08-4)
- Bis(4,5-dimethyl-1,2-benzenediamine-κN1)(4,5-dimethyl-1,2-benzenediamine-κN1,κN2)bis(2,2-dimethylpropanoato-κO)nickel(II) (CAS 1237501-56-2)
- Vericiguat Impurity 10 (CAS CATO-C4X-289610)
- Tucatinib Impurity 9 (CAS CATO-C4X-26059)
- Beraprost Impurity 31 (CAS CATO-C4X-218431)
- Mirogabalin Impurity 57 TFA (CAS CATO-C4X-292457)
- 3-Methyl-3H-[1,2,3]triazolo[4,5-d]pyrimidine-7-carboxylic acid (CAS 1095822-43-7)
- Ethyl (5-Ethyl-2-pyridinyl)acetate (CAS 99986-02-4)
- 1-Bromo-5-methylhex-3-ene (CAS 99113-56-1)
- Methotrexate Impurity 72 (CAS CATO-C4X-115472)
- 4-Ethyl-3-phenylfuran-2-carbohydrazide (CAS 576170-45-1)
- N-Methyl-4-nitrophthalimide (CAS 41663-84-7)
- [3,5 Diiodo-Tyr7] Peptide T (CAS 128551-40-6)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com