Elagolix Impurity 108 CAS 2486454-64-0
| CAS No. | 2486454-64-0 |
| Molecular Formula | C28H24F5N3O4 |
| Molecular Weight | 561.50 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
As a process- or degradation-related impurity, Elagolix Impurity 108 (CAS 2486454-64-0, C28H24F5N3O4) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
The molecular framework of Elagolix Impurity 108 (C28H24F5N3O4) is characterized by a steroid core, an amide group, a hydroxyl group, an ether linkage, fluorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
CATO manufactures Elagolix Impurity 108 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C28H24F5N3O4 |
| Molecular Weight | 561.50 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 16.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2000 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 3 |
Related Elagolix Standards
- Elagolix Impurity 21 (CAS CATO-C4X-206821)
- Elagolix lmpurity 61 (CAS 2486454-65-1)
- Elagolix Impurity 28 (CAS 2409132-63-2)
- Elagolix Impurity 51 (CAS CATO-C4X-206851)
- Elagolix Intermediate 29 (CAS 830346-50-4)
- S-Elagolix Impurity 6 (CAS 2756307-50-1)
- Elagolix Impurity 88 (CAS CATO-C4X-206888)
- Elagolix Impurity 8 (CAS 2409132-61-0)
Recommended Standards
- Bromo-PEG8-Boc (CAS 1623792-00-6)
- N-Cyclopropyl-4-[6-(2,3-difluoro-4-methoxyphenoxy)-8-[(3,3,3-trifluoropropyl)amino]imidazo[1,2-b]pyridazin-3-yl]-2-methylbenzamide (CAS 1554458-53-5)
- (2R,3S,Z)-6-Fluoro-N,N-bis(4-methoxybenzyl)-3-methyl-6-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)hex-5-ene-2-sulfonamide (CAS 2580245-78-7)
- lifitegrast Impurity 21 (CAS CATO-C4X-240921)
- Posaconazole Impurity 66 (CAS 165115-83-3)
- Oxybuprocaine Impurity 10 (CAS CATO-C4X-122710)
- Oxymetazoline Impurity 17 (CAS 756534-85-7)
- 5,6-Di(furan-2-yl)-3-propyl-2,2'-bipyridine (CAS 871798-94-6)
- N-Nitroso Formoterol (CAS CATO-C4X-152585)
- 3-(1-Isopropyl-1H-benzo[d]imidazol-2-yl)propanoic acid (CAS 1094345-74-0)
- 1-(Furan-2-ylmethyl)-2,5-dimethyl-1h-pyrrole-3-carbaldehyde (CAS 5049-49-0)
- tert-Butyl (3'-amino-[1,1'-biphenyl]-3-yl)carbamate (CAS 1228032-40-3)
- 4-Hydroxypicolinic Acid Hydrobromide (CAS 125545-96-2)
- Casein Kinase II Receptor Peptide (CAS 198481-81-1)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com