1-((Difluoromethyl)sulfonyl)-4-nitrobenzene CAS 24906-74-9
| CAS No. | 24906-74-9 |
| Molecular Formula | C7H5F2NO4S |
| Molecular Weight | 237.18 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
1-((Difluoromethyl)sulfonyl)-4-nitrobenzene (CAS 24906-74-9) is a high-purity analytical reference standard with the molecular formula C7H5F2NO4S and a molecular weight of 237.18 g/mol.
Owing to an amide group, a sulfone group, a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine substitution, an aromatic ring system, 1-((Difluoromethyl)sulfonyl)-4-nitrobenzene is typically off-white to pale yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 237.18 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
Physical & Chemical Properties
| Molecular Formula | C7H5F2NO4S |
| Molecular Weight | 237.18 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO, water |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1964 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 1 |
| Sulfur Atoms | 1 |
Related Difluoromethyl Standards
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Recommended Standards
- Ethyl 6-Oxo-2-(trifluoromethyl)-1,4,5,6-tetrahydropyridine-3-carboxylate (CAS 194673-12-6)
- 1-difluoromethanesulfonyl-3-nitrobenzene (CAS 24906-73-8)
- 2,2-difluoro-2H-1,3-benzodioxole-4-sulfonamide (CAS 1909347-73-4)
- 1-Phenyl-5-(trifluoromethyl)-1H-pyrazole-4-carbonitrile (CAS 318497-83-5)
- 1-((4-Chloro-3,5-dimethyl-1h-pyrazol-1-yl)methyl)-1,2-dihydro-3h-pyrazol-3-imine (CAS 1006472-80-5)
- 3,6-Dimethylbenzo[d]thiazol-2(3H)-imine (CAS 52853-54-0)
- 3-(2-Fluorophenoxy)propionic Acid (CAS 2967-72-8)
- 4-(2,4-Dimethoxyphenyl)-1-methylpyrrolidin-3-amine (CAS 1492429-38-5)
- 3,6-Diaminopyrazine-2,5-dicarbonitrile (CAS 133940-72-4)
- 1-Ethyl-6-fluoro-7-morpholino-4-oxo-1,4-dihydroquinoline-3-carboxylic acid (CAS 70458-98-9)
- 7-(Trifluoromethyl)quinolin-8-ol (CAS 313-17-7)
- 7-chloro-1H,2H,3H-pyrrolo[2,3-c]pyridine (CAS 1338219-65-0)
- 3-Thia-9-azaspiro[5.5]undecane 3,3-dioxide (CAS 1341853-52-8)
- Semaglutide impurity 54 (CAS CATO-C4X-222654)
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