7-(Trifluoromethyl)quinolin-8-ol CAS 313-17-7
| CAS No. | 313-17-7 |
| Molecular Formula | C10H6F3NO |
| Molecular Weight | 213.16 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
7-(Trifluoromethyl)quinolin-8-ol (CAS 313-17-7) is a high-purity analytical reference standard with the molecular formula C10H6F3NO and a molecular weight of 213.16 g/mol.
The molecular framework of 7-(Trifluoromethyl)quinolin-8-ol (C10H6F3NO) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
CATO manufactures 7-(Trifluoromethyl)quinolin-8-ol under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C10H6F3NO |
| Molecular Weight | 213.16 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 7.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1957 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 1 |
Related Trifluoromethyl Standards
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- 8-(Trifluoromethyl)isoquinolin-3-ol (CAS 1175271-71-2)
Recommended Standards
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- 7-(Trifluoromethyl)quinoxalin-2-amine (CAS 59489-42-8)
- 7-(Trifluoromethyl)quinolin-4(1H)-one (CAS 93516-03-1)
- 8-(Trifluoromethyl)quinolin-2(1H)-one (CAS 920494-30-0)
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