Fexofenadine Impurity 27 CAS 24911-30-6
| CAS No. | 24911-30-6 |
| Molecular Formula | C11H12O4 |
| Molecular Weight | 208.21 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Structurally, Fexofenadine Impurity 27 (C11H12O4) contains a carboxylic acid group, a hydroxyl group, an ether linkage, an aromatic ring system. The molecule exhibits a degree of unsaturation (DBE) of 6.0, corresponding to approximately 6 ring(s) or double-bond equivalent(s). With a molecular weight of 208.21 g/mol, it falls into the medium-molecular-weight range. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
Fexofenadine Impurity 27 (CAS 24911-30-6) is a certified pharmaceutical impurity reference standard with the molecular formula C11H12O4 and a molecular weight of 208.21 g/mol.
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C11H12O4 |
| Molecular Weight | 208.21 g/mol |
| Appearance | Off-white to pale yellow crystalline powder |
| Purity | >95% |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 6.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1964 |
Related Fexofenadine Standards
- Fexofenadine Impurity 26 (CAS 169280-26-6)
- Fexofenadine impurity 43 (CAS CATO-C4X-179443)
- Fexofenadine Impurity 21 (CAS 162096-54-0)
- Fexofenadine Impurity 18 (CAS 880088-78-8)
- Fexofenadine Impurity 10 (CAS CATO-C4X-179410)
- Fexofenadine Impurity 23 (CAS 169280-25-5)
- Fexofenadine Impurity 13 (CAS 88783-30-6)
- Fexofenadine EP Impurity E (CAS 115-46-8)
Recommended Standards
- Indobufen Impurity 85 (CAS CATO-C4X-179285)
- Etomidate Impurity 72 (CAS CATO-C4X-188472)
- Indobufen Impurity 73 (CAS CATO-C4X-179273)
- Esmolol Impurity 34 (CAS 7249-16-3)
- Lenalidomide Impurity 43 (CAS 1061604-41-8)
- Canagliflozin Impurity 89 (CAS CATO-C4X-112389)
- Ceritinib Impurity 48 (CAS CATO-C4X-104848)
- Ethyl 4-bromo-5-methylthiophene-2-carboxylate (CAS 1256286-44-8)
- 2-Chloro-1-(2-fluorophenyl)ethan-1-one (CAS 53688-17-8)
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- 6-(3-Chlorophenyl)-6,7-dihydro-5H-[1,3]dioxolo[4,5-f]isoindol-5-one (CAS 4993-79-7)
- Ethyl 2-methyl-5-(trifluoromethyl)nicotinate (CAS 1196156-18-9)
- 2-((4-(Methyl(phenyl)carbamoyl)phenyl)carbamoyl)benzoic acid (CAS 941463-97-4)
- Liraglutide (13-21) TFA Salt (CAS CATO-C4X-19928)
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