Esmolol Impurity 34 CAS 7249-16-3
| CAS No. | 7249-16-3 |
| Molecular Formula | C11H12O4 |
| Molecular Weight | 208.21 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
As a process- or degradation-related impurity, Esmolol Impurity 34 (CAS 7249-16-3, C11H12O4) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
Owing to a carboxylic acid group, a hydroxyl group, an ether linkage, an aromatic ring system, Esmolol Impurity 34 is typically off-white to pale yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 208.21 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
As a certified reference material (CRM), Esmolol Impurity 34 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C11H12O4 |
| Molecular Weight | 208.21 g/mol |
| Appearance | Off-white to pale yellow crystalline powder |
| Purity | >95% |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 6.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1959 |
Related Esmolol Standards
- Esmolol Impurity 53 (CAS 5535-03-5)
- Esmolol Impurity 60 (CAS CATO-C4X-189160)
- Esmolol Impurity 33 (CAS 27542-85-4)
- Esmolol Impurity 86 (CAS CATO-C4X-189186)
- Esmolol Impurity 75 (CAS CATO-C4X-189175)
- Esmolol Impurity 38 (CAS 55226-78-3)
- Esmolol Impurity 20 (CAS 2167848-51-1)
- Esmolol Impurity 39 (CAS 54965-55-8)
Recommended Standards
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- Fexofenadine Impurity 27 (CAS 24911-30-6)
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- Indobufen Impurity 85 (CAS CATO-C4X-179285)
- Sildenafil Impurity 99 (CAS CATO-C4X-112899)
- Ursodeoxycholic Acid impurity 78 (CAS CATO-C4X-142278)
- Liothyronine EP Impurity A-13C9-15N (CAS 1431868-11-9)
- Ethyl 4-amino-3-(3-chloro-4-fluorophenyl)-2-thioxo-2,3-dihydrothiazole-5-carboxylate (CAS 312922-20-6)
- 15516-47-9 2-(4-methylphenoxy)acetyl chloride KS-00001L6Q (CAS 15516-47-9)
- (5-Fluoro-2-(3-methyl-1H-pyrazol-1-yl)pyridin-4-yl)boronic acid (CAS 2225175-00-6)
- (1-((Difluoromethyl)sulfonyl)piperidin-4-yl)methanamine hydrochloride (CAS 1311317-54-0)
- tert-Butyl 5-chloro-1H-indazole-1-carboxylate (CAS 1337880-35-9)
- Zonisamide USP Related Compound C (CAS 1217201-89-2)
- Semaglutide impurity 30 (CAS CATO-C4X-222630)
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