2'-Fluoro-4'-iodoacetophenone CAS 249291-84-7
| CAS No. | 249291-84-7 |
| Molecular Formula | C8H6FIO |
| Molecular Weight | 264.04 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
2'-Fluoro-4'-iodoacetophenone (CAS 249291-84-7) is a high-purity analytical reference standard with the molecular formula C8H6FIO and a molecular weight of 264.04 g/mol.
The molecular framework of 2'-Fluoro-4'-iodoacetophenone (C8H6FIO) is characterized by a hydroxyl group, an ether linkage, fluorine/iodine substitution, an aromatic ring system. In reversed-phase chromatography, its retention is governed primarily by the polarity and ionization state of its functional groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
As a certified reference material (CRM), 2'-Fluoro-4'-iodoacetophenone meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C8H6FIO |
| Molecular Weight | 264.04 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at room temperature, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | F/I-containing |
Related Fluoro Standards
- 1-(2-Fluoro-5-iodophenyl)ethan-1-one (CAS 1159512-66-9)
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- 1-(3-Fluoro-5-iodophenyl)ethan-1-one (CAS 1393557-47-5)
- 1-(2-Fluoro-3-iodophenyl)ethanone (CAS 1628003-72-4)
- 1-(4-fluoro-3-iodophenyl)ethan-1-one (CAS 1824096-42-5)
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Recommended Standards
- 2-Fluoro-5-iodo-4-methylbenzaldehyde (CAS 2385987-18-6)
- 3-(Bromomethyl)-5-(trifluoromethyl)benzonitrile (CAS 669080-79-9)
- 2-Bromo-6-ethynyl-4-(trifluoromethyl)aniline (CAS 875306-22-2)
- 3-Bromo-4-methyl-5-(trifluoromethyl)benzonitrile (CAS 2383004-77-9)
- α，α，α＇，α＇-Tetrabromo-m-xylene (CAS 36323-28-1)
- 1,3-Benzenedicarboxylic acid, 1,3-diphenyl ester, polymer with 1,3-benzenedimethanamine and 1,6-hexanediamine (CAS 114535-87-4)
- 1-Chloro-n-cyclopropyl-n-ethylmethanesulfonamide (CAS 1341768-61-3)
- 3-Chloro-6-fluoro-2-(trifluoromethyl)benzaldehyde (CAS 95399-94-3)
- Methyl 1-tosyl-1H-pyrrolo[2,3-b]pyridine-3-carboxylate (CAS 952182-23-9)
- 6-(3-Chlorophenyl)-4-phenyl-2-(3-(piperidin-1-yl)propyl)pyridazin-3(2H)-one (CAS 23348-19-8)
- 5-Chloro-2-(4-Piperonyl-1-Piperazinyl)Pyrimidine (CAS 21280-23-9)
- (R)-3-((Tert-butoxycarbonyl)amino)-3-(2,3-dimethoxyphenyl)propanoic acid (CAS 500788-92-1)
- Loxapine D8 (CAS 1189455-63-7)
- Semaglutide impurity 198 (CAS CATO-C4X-2226198)
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