3-Chloro-6-fluoro-2-(trifluoromethyl)benzaldehyde CAS 95399-94-3
| CAS No. | 95399-94-3 |
| Molecular Formula | C8H3ClF4O |
| Molecular Weight | 226.56 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The molecular framework of 3-Chloro-6-fluoro-2-(trifluoromethyl)benzaldehyde (C8H3ClF4O) is characterized by a hydroxyl group, an ether linkage, fluorine/chlorine substitution, an aromatic ring system. In reversed-phase chromatography, its retention is governed primarily by the polarity and ionization state of its functional groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
3-Chloro-6-fluoro-2-(trifluoromethyl)benzaldehyde (CAS 95399-94-3), molecular formula C8H3ClF4O and molecular weight 226.56 g/mol, is a CATO reference standard with documented purity and traceability.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
CATO manufactures 3-Chloro-6-fluoro-2-(trifluoromethyl)benzaldehyde under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C8H3ClF4O |
| Molecular Weight | 226.56 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at room temperature, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1984 |
| Halogen Content | F/Cl-containing |
Related Chloro Standards
- 5-Chloro-2-fluoro-3-(trifluoromethyl)benzaldehyde (CAS 117752-05-3)
- 1-(2-Chloro-6-fluorophenyl)-2,2,2-trifluoroethan-1-one (CAS 1208077-59-1)
- 3-Chloro-2-fluoro-4-(trifluoromethyl)benzaldehyde (CAS 134099-21-1)
- 5-Chloro-4-fluoro-2-(trifluoromethyl)benzaldehyde (CAS 134099-23-3)
- 2-Chloro-4-fluoro-6-(trifluoromethyl)benzaldehyde (CAS 134099-27-7)
- 3-Chloro-4-fluoro-5-(trifluoromethyl)benzaldehyde (CAS 134099-29-9)
- 5-Chloro-2-fluoro-4-(trifluoromethyl)benzaldehyde (CAS 134099-32-4)
- 2-Chloro-1-(3,4-difluorophenyl)-2,2-difluoroethan-1-one (CAS 1352215-14-5)
Recommended Standards
- 3-Chloro-4-(trifluoromethyl)benzoyl fluoride (CAS 320-62-7)
- 2-Fluoro-5-(trifluoromethyl)benzoyl chloride 2-fluoro-5-trifluoromethylbenzoyl chloride 2-fluoro-5-trifluoromethylbenzoylchloride 2-fluoro-5-(trifluoromethyl)benzoylchloride 207981-46-2 (CAS 207981-46-2)
- 3-Chloro-2-fluoro-5-(trifluoromethyl)benzaldehyde (CAS 261763-02-4)
- 216144-68-2 3-FLUORO-4-(TRIFLUOROMETHYL)BENZOYL CHLORIDE 3-Fluoro-4-(trifluoromethyl)benzoylchloride ALPHA,ALPHA,ALPHA,4-TETRAFLUORO-P-TOLUOYL CHLORIDE AS00072 (CAS 216144-68-2)
- 2-Methoxy-6-(4-methoxyphenethyl)benzoic acid (CAS 36640-14-9)
- (R)-6-(2-(4-Fluorophenyl)-6-(hydroxymethyl)-4,5,6,7-tetrahydropyrazolo-[1,5-a]pyrimidin-3-yl)-2-o-tolylpyridazin-3(2H)-one (CAS 928344-12-1)
- Potassium 2-(trifluoromethyl)benzenesulfonate (CAS 917560-97-5)
- 1-(2-Fluoroethyl)-5-methyl-N-((1-methyl-1H-pyrrol-2-yl)methyl)-1H-pyrazol-4-amine hydrochloride (CAS 1856075-91-6)
- 4-(Cyanomethyl)-3-nitrobenzoic acid (CAS 104825-24-3)
- C46NGD2HM7 875-35-4 2,6-Dichloro-4-methylnicotinonitrile EINECS 212-873-7 UNII-C46NGD2HM7 3-Cyano-2,6-dichloro-4-methylpyridine (CAS 875-35-4)
- 4-Methyl-1,8-naphthyridin-2-ol (CAS 889940-20-9)
- 3-(3-Methoxyphenyl)-5-(2-methyl-1,3-dioxolan-2-yl)benzo[c]isoxazole (CAS 439094-65-2)
- Cyclizine Hydrochloride (CAS 303-25-3)
- Semaglutide impurity 25 (CAS CATO-C4X-222625)
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