5-(((3-Chloro-5-(trifluoromethyl)pyridin-2-yl)amino)methyl)-4,5-dihydroisoxazole-3-carboxylic acid CAS 251097-82-2
| CAS No. | 251097-82-2 |
| Molecular Formula | C11H9ClF3N3O3 |
| Molecular Weight | 323.66 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
5-(((3-Chloro-5-(trifluoromethyl)pyridin-2-yl)amino)methyl)-4,5-dihydroisoxazole-3-carboxylic acid (C11H9ClF3N3O3) contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution. It is notably hygroscopic, halogen substitution raises its density and boiling point, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
5-(((3-Chloro-5-(trifluoromethyl)pyridin-2-yl)amino)methyl)-4,5-dihydroisoxazole-3-carboxylic acid (CAS 251097-82-2), molecular formula C11H9ClF3N3O3 and molecular weight 323.66 g/mol, is a CATO reference standard with documented purity and traceability.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C11H9ClF3N3O3 |
| Molecular Weight | 323.66 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 7.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 3 |
Related Chloro Standards
- (E)-4-(2-(3-chloro-5-(trifluoromethyl)pyridin-2-yl)-2-methylhydrazinyl)-4-oxobut-2-enoic acid (CAS 339110-32-6)
- 2-((1-(3-Chloro-5-(trifluoromethyl)pyridin-2-yl)-1H-pyrazol-5-yl)methylene)malononitrile (CAS 318248-55-4)
- 6-[3-Chloro-5-(trifluoromethyl)pyridin-2-yl]pyrazolo[1,5-a]pyrimidine-3-carbonitrile (CAS 338793-43-4)
- N-(2-Chloro-6-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzyl)butan-1-amine (CAS 2096334-51-7)
- N-(2-Chloro-6-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzyl)-n-ethylethanamine (CAS 2096332-20-4)
- N-(3-Chloro-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzyl)-2-methylpropan-2-amine (CAS 2096337-36-7)
- N-(3-Chloro-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzyl)-N-ethylethanamine (CAS 2096341-19-2)
- N-(4-Chloro-3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzyl)-2-methylpropan-2-amine (CAS 2096333-91-2)
Recommended Standards
- (Z)-N-(1-((3-chloro-5-(trifluoromethyl)pyridin-2-yl)methyl)imidazolidin-2-ylidene)nitramide (CAS 1781254-33-8)
- 7-Chloro-2-ethyl-6-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzo[d]thiazole (CAS 2409580-00-1)
- 3-Methyl-5-((2,3,6-trichlorobenzyl)thio)-4H-1,2,4-triazol-4-amine (CAS 449745-58-8)
- Tetrakis(ethylmethylamino)zirconium(IV) (CAS 175923-04-3)
- 2-Chloro-6-fluoro-3-nitrobenzaldehyde (CAS 899821-26-2)
- (S)-2-(6-Chloropyridin-3-yl)-4-((1-methoxypropan-2-yl)oxy)-N-(6-methylpyridin-3-yl)-7,8-dihydropyrido[4,3-d]pyrimidine-6(5H)-carboxamide (CAS 1257051-62-9)
- 2-(2-Methyl-1H-benzo[d]imidazol-1-yl)acetic acid hydrochloride (CAS 1177310-33-6)
- (S)-4-(2-Bromo-4-cyanophenyl)-1-(tert-butoxy-carbonyl)piperazine-2-carboxylic acid (CAS 1786489-53-9)
- N-(3-(1H-imidazol-1-yl)propyl)-5-chloro-4-methylbenzo[d]thiazol-2-amine (CAS 1177300-68-3)
- Tretinoin Impurity 21 (CAS CATO-C4X-196921)
- N-(bicyclo[2.2.1]Heptan-2-yl)-1-methyl-1H-pyrazol-3-amine (CAS 1251112-89-6)
- Aprepitant Impurity 39 (CAS 176306-78-8)
- 5-(4-Chlorophenyl)-4-hydrazinylthieno[2,3-d]pyrimidine (CAS 330473-50-2)
- Semaglutide Impurity 176 (CAS CATO-C4X-2226176)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com