2-((1-(3-Chloro-5-(trifluoromethyl)pyridin-2-yl)-1H-pyrazol-5-yl)methylene)malononitrile CAS 318248-55-4
| CAS No. | 318248-55-4 |
| Molecular Formula | C13H5ClF3N5 |
| Molecular Weight | 323.66 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
2-((1-(3-Chloro-5-(trifluoromethyl)pyridin-2-yl)-1H-pyrazol-5-yl)methylene)malononitrile (CAS 318248-55-4), molecular formula C13H5ClF3N5 and molecular weight 323.66 g/mol, is a CATO reference standard with documented purity and traceability.
Owing to a nitrogen-containing heterocyclic scaffold, a nitrile group, fluorine/chlorine substitution, 2-((1-(3-Chloro-5-(trifluoromethyl)pyridin-2-yl)-1H-pyrazol-5-yl)methylene)malononitrile is typically pale yellow to yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 323.66 g/mol — guide the selection of appropriate sample preparation and analytical techniques. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
CATO manufactures 2-((1-(3-Chloro-5-(trifluoromethyl)pyridin-2-yl)-1H-pyrazol-5-yl)methylene)malononitrile under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C13H5ClF3N5 |
| Molecular Weight | 323.66 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 12.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 5 |
Related Chloro Standards
- (E)-4-(2-(3-chloro-5-(trifluoromethyl)pyridin-2-yl)-2-methylhydrazinyl)-4-oxobut-2-enoic acid (CAS 339110-32-6)
- 5-(((3-Chloro-5-(trifluoromethyl)pyridin-2-yl)amino)methyl)-4,5-dihydroisoxazole-3-carboxylic acid (CAS 251097-82-2)
- 6-[3-Chloro-5-(trifluoromethyl)pyridin-2-yl]pyrazolo[1,5-a]pyrimidine-3-carbonitrile (CAS 338793-43-4)
- N-(2-Chloro-6-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzyl)butan-1-amine (CAS 2096334-51-7)
- N-(2-Chloro-6-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzyl)-n-ethylethanamine (CAS 2096332-20-4)
- N-(3-Chloro-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzyl)-2-methylpropan-2-amine (CAS 2096337-36-7)
- N-(3-Chloro-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzyl)-N-ethylethanamine (CAS 2096341-19-2)
- N-(4-Chloro-3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzyl)-2-methylpropan-2-amine (CAS 2096333-91-2)
Recommended Standards
- (Z)-N-(1-((3-chloro-5-(trifluoromethyl)pyridin-2-yl)methyl)imidazolidin-2-ylidene)nitramide (CAS 1781254-33-8)
- 7-Chloro-2-ethyl-6-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzo[d]thiazole (CAS 2409580-00-1)
- 3-Methyl-5-((2,3,6-trichlorobenzyl)thio)-4H-1,2,4-triazol-4-amine (CAS 449745-58-8)
- Tetrakis(ethylmethylamino)zirconium(IV) (CAS 175923-04-3)
- 3-Nitroimidazo[1,2-a]pyridine-2-carbonitrile (CAS 62195-05-5)
- Antimony(III) Selenide (CAS 1315-05-5)
- N-((1R,2R)-1-Hydroxy-1-((4R,5R)-5-hydroxy-2-phenyl-1,3-dioxan-4-yl)-3-oxopropan-2-yl)acetamide (CAS 420118-03-2)
- Methyl 5-((2-ethoxyphenyl)carbamoyl)-4-methyl-2-(2-(thiophen-2-yl)acetamido)thiophene-3-carboxylate (CAS 505096-52-6)
- Methyl 1-(pyridin-3-yl)-2,3,4,9-tetrahydro-1H-pyrido[3,4-b]indole-3-carboxylate (CAS 84133-32-4)
- 1-Allyl-5-bromopyrimidine-2,4(1H,3H)-dione (CAS 195508-02-2)
- trans-Stilbene-d10 (rings-d10) (CAS 20748-24-7)
- N-(2,5-Dimethoxyphenyl)-5-methylisoxazole-3-carboxamide (CAS 145440-98-8)
- (S)-1-benzyl-N-methylpiperidin-3-amine (CAS 1354001-42-5)
- Neuropeptide Y (3-36) (porcine) trifluoroacetate salt (CAS 143863-88-1)
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