Brexpiprazole Impurity 154 CAS 2514958-62-2
| CAS No. | 2514958-62-2 |
| Molecular Formula | C13H14BrNO2 |
| Molecular Weight | 296.16 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
As a certified reference material (CRM), Brexpiprazole Impurity 154 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
CATO supplies Brexpiprazole Impurity 154 (CAS 2514958-62-2), a pharmacopoeial impurity reference standard (molecular formula C13H14BrNO2, MW 296.16 g/mol) used for the identification and quantification of trace impurities in APIs.
Structurally, Brexpiprazole Impurity 154 (C13H14BrNO2) contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, bromine substitution. The molecule exhibits a degree of unsaturation (DBE) of 7.0, corresponding to approximately 7 ring(s) or double-bond equivalent(s). With a molecular weight of 296.16 g/mol, it falls into the medium-molecular-weight range. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
Physical & Chemical Properties
| Molecular Formula | C13H14BrNO2 |
| Molecular Weight | 296.16 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor) |
| Purity | ≥95% |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 7.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2000 |
| Halogen Content | Br-containing |
| Nitrogen Atoms | 1 |
Related Brexpiprazole Standards
- Brexpiprazole Impurity 14 (CAS 203395-59-9)
- Brexpiprazole Impurity 162 (CAS CATO-C4X-1131162)
- Brexpiprazole Impurity 136 (CAS 2657666-89-0)
- Brexpiprazole Impurity 29 (CAS 913614-15-0)
- Brexpiprazole impurity 112 (CAS CATO-C4X-1131112)
- Brexpiprazole Impurity 140 (CAS CATO-C4X-1131140)
- Brexpiprazole Impurity 133 (CAS 1268367-99-2)
- Brexpiprazole Impurity 164 (CAS CATO-C4X-1131164)
Recommended Standards
- tert-Butyl 7-bromo-1H-indole-1-carboxylate (CAS 868561-17-5)
- 1-(2-(2-Methoxyethoxy)ethyl)-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrazole (CAS 1185767-91-2)
- tert-Butyl 5-bromo-1H-indole-2-carboxylate (CAS 2502205-56-1)
- 4'-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-[1,1'-biphenyl]-2-ol (CAS 1219741-54-4)
- Ibuprofen impurity 124 (CAS CATO-C4X-1082124)
- Peridine Impurity 8 Dihydrochloride (CAS 76508-73-1)
- Tedizolid Impurity 51 (CAS CATO-C4X-105451)
- 2-Chloro-5-methylpyrimidine-4-carboxamide (CAS 2751646-32-7)
- Boc-PEG8-Boc (CAS 1432970-18-7)
- 3-Amino-1-(4-methoxyphenyl)-1H-pyrazol-5(4H)-one (CAS 24630-93-1)
- 6-Bromo-5-nitro-2-pyridinemethanamine (CAS 914224-00-3)
- 1-N-Butyl-1-N-methylbenzene-1,4-diamine (CAS 104178-20-3)
- 6-Amino-4-fluoronicotinic acid (CAS 1805876-31-6)
- Semaglutide impurity 97 (CAS CATO-C4X-222697)
Why CATO?
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