Ritonavir Impurity N11 CAS 2519851-81-9
| CAS No. | 2519851-81-9 |
| Molecular Formula | C14H23N3O4S |
| Molecular Weight | 329.42 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Ritonavir Impurity N11 (CAS 2519851-81-9) is a certified pharmaceutical impurity reference standard with the molecular formula C14H23N3O4S and a molecular weight of 329.42 g/mol.
Based on its molecular formula C14H23N3O4S, Ritonavir Impurity N11 contains a nitrogen-containing heterocyclic scaffold, an amide group, a sulfone group, a hydroxyl group, an ether linkage; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 329.42 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
Physical & Chemical Properties
| Molecular Formula | C14H23N3O4S |
| Molecular Weight | 329.42 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2000 |
| Nitrogen Atoms | 3 |
| Sulfur Atoms | 1 |
Related Ritonavir Standards
- Ritonavir Impurity 52 (CAS CATO-C4X-175152)
- Ritonavir Impurity 53 (CAS CATO-C4X-175153)
- Ritonavir EP Impurity A (CAS 154212-61-0)
- Ritonavir Impurity N16 (CAS 183246-46-0)
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