Rabeprazole Impurity 7 CAS 117976-91-7
| CAS No. | 117976-91-7 |
| Molecular Formula | C17H19N3O2S |
| Molecular Weight | 329.42 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
Rabeprazole Impurity 7 (CAS 117976-91-7) is a certified pharmaceutical impurity reference standard with the molecular formula C17H19N3O2S and a molecular weight of 329.42 g/mol.
The molecular framework of Rabeprazole Impurity 7 (C17H19N3O2S) is characterized by a steroid core, an amide group, a sulfone group, a hydroxyl group, an ether linkage. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
As a certified reference material (CRM), Rabeprazole Impurity 7 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C17H19N3O2S |
| Molecular Weight | 329.42 g/mol |
| Purity | >95% |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 10.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1990 |
| Nitrogen Atoms | 3 |
| Sulfur Atoms | 1 |
Related Rabeprazole Standards
- Rabeprazole 4-Chloro Analog Sulfone (CAS 1159977-27-1)
- Rabeprazole Impurity 30 (CAS 1807988-36-8)
- Rabeprazole 4-Methylthio Analog (CAS 99487-86-2)
- Rabeprazole Impurity 17(See C4X-112130) (CAS CATO-C4X-112117)
- Rabeprazole EP Impurity B (CAS 117977-21-6)
- Rabeprazole Impurity 44 (CAS CATO-C4X-112144)
- Rabeprazole Impurity 27 (CAS 117976-94-0)
- Rabeprazole-d3 Sulfide (CAS 1185084-49-4)
Recommended Standards
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- Netilmicin EP Impurity C (CAS 63721-52-8)
- Spiramycin EP Impurity B (CAS 249930-66-3)
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- Resmetirom impurity 80 (CAS CATO-C4X-291280)
- 1,3-Dimethyl 2-{4-[ethyl(phenyl)sulfamoyl]-2-nitrophenyl}propanedioate (CAS 860785-57-5)
- 6-(Pyridin-2-yloxy)-2-azaspiro[3.3]heptane (CAS 1779128-70-9)
- 1-Phenylbut-3-yn-1-ol (CAS 1743-36-8)
- 5,7-Dichloro-N-(4-methoxyphenyl)thiazolo[4,5-d]pyrimidine-2-sulfonamide (CAS 1000575-54-1)
- (Des-His1,Glu?)-Glucagon (1-29) amide (human, rat, porcine) (CAS 110084-95-2)
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