1-Bromo-2,5-difluoro-4-methylbenzene CAS 252004-42-5
| CAS No. | 252004-42-5 |
| Molecular Formula | C7H5BrF2 |
| Molecular Weight | 207.02 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
1-Bromo-2,5-difluoro-4-methylbenzene (CAS 252004-42-5), molecular formula C7H5BrF2 and molecular weight 207.02 g/mol, is a CATO reference standard with documented purity and traceability.
1-Bromo-2,5-difluoro-4-methylbenzene (C7H5BrF2) contains fluorine/bromine substitution, an aromatic ring system. Halogen substitution raises its density and boiling point; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), 1-Bromo-2,5-difluoro-4-methylbenzene meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C7H5BrF2 |
| Molecular Weight | 207.02 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at room temperature, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO |
| Stability | May oxidize slowly on prolonged air exposure |
| Degree of Unsaturation (DBE) | 4.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | F/Br-containing |
Related Bromo Standards
- 3-Bromo-4,5-difluorotoluene (CAS 1143502-74-2)
- 5-Bromo-1,2-difluoro-3-methylbenzene (CAS 1143502-75-3)
- 2-Bromo-3,6-difluorotoluene (CAS 1208074-75-2)
- 1-Bromo-2,5-difluoro-3-methylbenzene (CAS 1416354-32-9)
- 5-Bromo-2,4-difluorotoluene (CAS 159277-47-1)
- 1-Bromo-3-fluoro-5-(fluoromethyl)benzene (CAS 1715032-20-4)
- 1-Bromo-3-fluoro-2-(fluoromethyl)benzene (CAS 1782526-83-3)
- 2-Bromo-1-fluoro-4-(fluoromethyl)benzene (CAS 1783551-07-4)
Recommended Standards
- 1-Bromo-2,3-difluoro-4-methylbenzene (CAS 928304-47-6)
- 1-Bromo-3-(difluoromethyl)benzene (CAS 29848-59-7)
- (Bromodifluoromethyl)benzene (CAS 83170-17-6)
- 1-Bromo-4,5-difluoro-2-methylbenzene (CAS 875664-38-3)
- 1261819-46-8 2-Bromo-4-(difluoromethyl)aniline (CAS 1261819-46-8)
- (+)-(3-Bromopropyl)boronic Acid Pinanediol Ester (CAS 90084-37-0)
- 1-Butoxy-4-chloro-2,5-difluorobenzene (CAS 1881288-09-0)
- Lovastatin Impurity 7 (CAS 79394-47-1)
- 2-((7-(4-(Di-p-tolylamino)phenyl)benzo[c][1,2,5]thiadiazol-4-yl)methylene)malononitrile (CAS 1393343-58-2)
- 2-Acetylcyclopent-4-ene-1,3-dione (CAS 4056-67-1)
- Copper(I) tetrafluoroborate (CAS 14708-11-3)
- n-(Pyrimidin-5-ylmethyl)aniline (CAS 768383-69-3)
- 5-(hydroxymethyl)pyridine-3-carbonitrile (CAS 135124-71-9)
- Tirzepatide Impurity 17 (CAS CATO-C4X-324017)
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