Fmoc-His(3-Me)-OH CAS 252049-16-4
| CAS No. | 252049-16-4 |
| Molecular Formula | C22H21N3O4 |
| Molecular Weight | 391.43 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
Fmoc-His(3-Me)-OH (CAS 252049-16-4) is a high-purity analytical reference standard with the molecular formula C22H21N3O4 and a molecular weight of 391.43 g/mol.
Structurally, Fmoc-His(3-Me)-OH (C22H21N3O4) contains a flavonoid core, an amide group, a hydroxyl group, an ether linkage. The molecule exhibits a degree of unsaturation (DBE) of 14.0, corresponding to approximately 14 ring(s) or double-bond equivalent(s). With a molecular weight of 391.43 g/mol, it falls into the moderately-high-molecular-weight range. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
As a certified reference material (CRM), Fmoc-His(3-Me)-OH meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C22H21N3O4 |
| Molecular Weight | 391.43 g/mol |
| Appearance | Pale yellow to yellow crystalline powder |
| Purity | >95% |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 14.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Nitrogen Atoms | 3 |
Related Fmoc Standards
- Fmoc-D-His(1-Me)-OH (CAS 1197025-85-6)
- Fmoc-D-His(3-Me)-OH (CAS 2002499-17-2)
- Fmoc-His-OMe (CAS 160450-10-2)
- Fmoc-His(1-Me)-OH (CAS 202920-22-7)
- (2S)-1-Fmoc-octahydro-1H-indole-2-carboxylic Acid (CAS 214750-71-7)
- Fmoc-L-Ala(cyclohexen-1-yl)-OH (CAS 2348299-84-1)
- Fmoc-L-octahydroindole-2-carboxylic acid (CAS 130309-37-4)
- Fmoc-4-fluoro-D-phenylglycine (CAS 374791-03-4)
Recommended Standards
- 1-(2-(4-Ethylphenoxy)acetyl)-4-((4-methylphenyl)sulfonyl)semicarbazide (CAS 1024439-41-5)
- Ponatinib Impurity 9 (CAS CATO-C4X-22699)
- 2-(6,7-Dimethoxy-2-(phenylsulfonyl)-1,2,3,4-tetrahydroisoquinolin-1-yl)acetic acid (CAS 10447-22-0)
- Ponatinib Impurity 31 (CAS CATO-C4X-226931)
- 8-Methyl-1,2,3,4-tetrahydroisoquinoline (CAS 129961-74-6)
- Trimethyl((1-phenoxyprop-1-en-1-yl)oxy)silane (CAS 65946-50-1)
- 2-(m-Tolyl)benzo[d]thiazole (CAS 1211-32-1)
- Dalbavancin Impurity 8 (CAS CATO-C4X-16028)
- Hexanal-d12 (CAS 1219803-74-3)
- 2-Ethylhexanoic acid (CAS 25103-52-0)
- 2-(Difluoromethyl)benzo[d]oxazole-4-carboxaldehyde (CAS 1804192-31-1)
- 87827-55-2 Alismol 1-Azulenol, 1,2,3,3a,4,5,6,8a-octahydro-1-methyl-4-methylene-7-(1-methylethyl)-, (1R-(1alpha,3abeta,8abeta))- (CAS 87827-55-2)
- N-cyclopropylpyridazin-3-amine (CAS 1250068-48-4)
- Semaglutide impurity 85 (CAS CATO-C4X-222685)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com