Lumefantrine Impurity 7 CAS 2523-44-6
| CAS No. | 2523-44-6 |
| Molecular Formula | C13H9Cl |
| Molecular Weight | 200.66 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of Lumefantrine Impurity 7 is closely related to chlorine substitution, an aromatic ring system in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
Lumefantrine Impurity 7 (CAS 2523-44-6) is a certified pharmaceutical impurity reference standard with the molecular formula C13H9Cl and a molecular weight of 200.66 g/mol.
Structurally, Lumefantrine Impurity 7 (C13H9Cl) contains chlorine substitution, an aromatic ring system. The molecule exhibits a degree of unsaturation (DBE) of 9.0, corresponding to approximately 9 ring(s) or double-bond equivalent(s). With a molecular weight of 200.66 g/mol, it falls into the medium-molecular-weight range. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
As a certified reference material (CRM), Lumefantrine Impurity 7 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C13H9Cl |
| Molecular Weight | 200.66 g/mol |
| Purity | >95% |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 9.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1957 |
| Halogen Content | Cl-containing |
Related Lumefantrine Standards
- Lumefantrine Impurity 10 (CAS 934748-28-4)
- Lumefantrine Impurity 9 (CAS 7061-81-6)
- Lumefantrine Epoxide (CAS 53221-14-0)
- Lumefantrine Impurity 3 (CAS 4364-35-6)
- Lumefantrine DBA Impurity (CAS 53221-07-1)
- Lumefantrine Impurity N1 (CAS 2170653-95-7 (free base))
- Lumefantrine Impurity 12 (CAS CATO-C4X-242612)
- Lumefantrine Impurity 2 (CAS 355841-11-1(Free base))
Recommended Standards
- Bevantolol Impurity 6 (CAS 42865-04-3)
- 9-Chlorofluorene (CAS 6630-65-5)
- Tulobuterol Impurity 21 (CAS CATO-C4X-213421)
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- 7-Bromo-9H-pyrido[3,4-b]indole (CAS 88704-40-9)
- AZD-7594 (CAS 1196509-60-0)
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- cis-4-azidocyclohexanecarboxylic acid (CAS 863222-21-3)
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