Lumefantrine Epoxide CAS 53221-14-0
| CAS No. | 53221-14-0 |
| Molecular Formula | C15H10Cl2O |
| Molecular Weight | 277.15 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including Lumefantrine Epoxide.
CATO supplies Lumefantrine Epoxide (CAS 53221-14-0), a certified reference material (molecular formula C15H10Cl2O, MW 277.15 g/mol) for analytical method development and quality control.
Structurally, Lumefantrine Epoxide (C15H10Cl2O) contains a hydroxyl group, an ether linkage, chlorine substitution, a polycyclic aromatic system. The molecule exhibits a degree of unsaturation (DBE) of 10.0, corresponding to approximately 10 ring(s) or double-bond equivalent(s). With a molecular weight of 277.15 g/mol, it falls into the medium-molecular-weight range. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C15H10Cl2O |
| Molecular Weight | 277.15 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 10.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1972 |
| Halogen Content | Cl-containing |
Related Lumefantrine Standards
- Lumefantrine Impurity 9 (CAS 7061-81-6)
- Lumefantrine Impurity 10 (CAS 934748-28-4)
- Lumefantrine Impurity 7 (CAS 2523-44-6)
- Lumefantrine Impurity 3 (CAS 4364-35-6)
- Lumefantrine Impurity 11 (CAS CATO-C4X-242611)
- Lumefantrine Impurity 5 (CAS 69759-61-1)
- Lumefantrine Impurity 6 (CAS 355841-11-1)
- Lumefantrine impurity 7 (CAS CATO-C4X-24267)
Recommended Standards
- Anagrelide USP Related Compound A (CAS 70406-92-7)
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- 2,3-Difluoro-6-isopropoxybenzaldehyde (CAS 949026-89-5)
- 3-Amino-3-methylpiperidine-2,6-dione (CAS 202271-85-0)
- (2S)-2-amino-2-methyl-3-(2-naphthyl)propanoic acid (CAS 145232-47-9)
- 1-(4-PYridinylmethyl)-1h-pyrrole-2-carbaldehyde oxalate (2:1) (CAS 1415819-91-8)
- Semaglutide Main Chain P29 (CAS 1169630-82-3)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com