2-((tert-Butoxycarbonyl)amino)-4,4-difluorobutanoic acid CAS 252357-43-0
| CAS No. | 252357-43-0 |
| Molecular Formula | C9H15F2NO4 |
| Molecular Weight | 239.22 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The molecular framework of 2-((tert-Butoxycarbonyl)amino)-4,4-difluorobutanoic acid (C9H15F2NO4) is characterized by an amide group, a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
CATO supplies 2-((tert-Butoxycarbonyl)amino)-4,4-difluorobutanoic acid (CAS 252357-43-0), a certified reference material (molecular formula C9H15F2NO4, MW 239.22 g/mol) for analytical method development and quality control.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), 2-((tert-Butoxycarbonyl)amino)-4,4-difluorobutanoic acid meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C9H15F2NO4 |
| Molecular Weight | 239.22 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO |
| Stability | Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 2.0 |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 1 |
Related tert Standards
- 3-((tert-Butoxycarbonyl)amino)-4,4-difluorobutanoic acid (CAS 81982-56-1)
- 4-((Tert-butoxycarbonyl)amino)-2,2-difluorobutanoic acid (CAS 2166810-88-2)
- 2-((tert-Butoxycarbonyl)amino)pyrimidine-5-carboxylic acid (CAS 179322-60-2)
- 2-((tert-Butoxycarbonyl)amino)pyrimidine-4-carboxylic acid (CAS 2248314-44-3)
- 3-((Tert-butoxycarbonyl)amino)pyrazine-2-carboxylic acid (CAS 941316-90-1)
- 4-((tert-Butoxycarbonyl)amino)pyrimidine-5-carboxylic acid (CAS 2248287-04-7)
- 5-((tert-Butoxycarbonyl)amino)pyrazine-2-carboxylic acid (CAS 891782-63-1)
- 5-((tert-Butoxycarbonyl)amino)pyrimidine-2-carboxylic acid (CAS 2384916-52-1)
Recommended Standards
- 1,2-Dichlorododecane (CAS 75121-23-2)
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- 2-(3-Methyl-4-nitrophenoxy)butanoic acid (CAS 869948-84-5)
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- 2-((5-Bromobenzo[d]isoxazol-3-yl)oxy)acetic acid (CAS 1708288-69-0)
- 5-(Methylthio)-4H-thieno[3,2-b]pyrrole (CAS 102788-09-0)
- n-(2-(Methylamino)ethyl)-2-nitrobenzenesulfonamide (CAS 1465047-64-6)
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- tert-Butyl 2-(ethyl-13C2)-2-hydroxypyrrolidine-1-carboxylate (CAS 1391053-12-5)
- FLAG Epitope Peptide (CAS 98849-88-8)
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