tert-Butyl N-(4,4-difluoro-1-oxobutan-2-yl)carbamate CAS 252357-36-1
| CAS No. | 252357-36-1 |
| Molecular Formula | C9H15F2NO3 |
| Molecular Weight | 223.22 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
CATO supplies tert-Butyl N-(4,4-difluoro-1-oxobutan-2-yl)carbamate (CAS 252357-36-1), a certified reference material (molecular formula C9H15F2NO3, MW 223.22 g/mol) for analytical method development and quality control.
tert-Butyl N-(4,4-difluoro-1-oxobutan-2-yl)carbamate (C9H15F2NO3) contains an amide group, a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine substitution. It is notably hygroscopic, halogen substitution raises its density and boiling point, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
Physical & Chemical Properties
| Molecular Formula | C9H15F2NO3 |
| Molecular Weight | 223.22 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO |
| Stability | Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 2.0 |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 1 |
Recommended Standards
- Tert-butyl (R)-3,3-difluoro-4-hydroxypyrrolidine-1-carboxylate (CAS 2165974-26-3)
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- tert-Butyl (R)-3,3-difluoro-2-(hydroxymethyl)azetidine-1-carboxylate (CAS 2810050-57-6)
- Miglitol impurity N2 (CAS 2230722-74-2)
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