4-Ethoxy-3-(trifluoromethyl)benzoic acid CAS 252901-50-1
| CAS No. | 252901-50-1 |
| Molecular Formula | C10H9F3O3 |
| Molecular Weight | 234.17 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
4-Ethoxy-3-(trifluoromethyl)benzoic acid (C10H9F3O3) contains a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine substitution, an aromatic ring system. It is notably hygroscopic, halogen substitution raises its density and boiling point, its high carbon-to-hydrogen ratio confers good lipid solubility, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
CATO supplies 4-Ethoxy-3-(trifluoromethyl)benzoic acid (CAS 252901-50-1), a certified reference material (molecular formula C10H9F3O3, MW 234.17 g/mol) for analytical method development and quality control.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), 4-Ethoxy-3-(trifluoromethyl)benzoic acid meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C10H9F3O3 |
| Molecular Weight | 234.17 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | F-containing |
Related Ethoxy Standards
- 3-Ethoxy-5-(trifluoromethyl)benzoic acid (CAS 1310416-50-2)
- 4-Ethoxy-2-(trifluoromethyl)benzoic acid (CAS 1340229-02-8)
- 1-(5-Ethoxy-2-hydroxyphenyl)-2,2,2-trifluoroethan-1-one (CAS 730992-69-5)
- 2-(6-Ethoxy-2,3,4-trifluorophenyl)acetic acid (CAS 1980062-56-3)
- 2-Ethoxy-5-(trifluoromethyl)benzoic acid (CAS 472809-65-7)
- 6-Ethoxy-2-oxo-2H-chromene-4-carboxylic acid (CAS 1355193-91-7)
- 7-Ethoxy-2-oxo-2H-chromene-3-carboxylic acid (CAS 79065-74-0)
- 8-Ethoxy-2-oxo-2H-1-benzopyran-3-carboxylic acid (CAS 81017-24-5)
Recommended Standards
- 4-Bromo-3-methyl-5-trimethylsilanyl-isoxazole (CAS 54773-30-7)
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- 3-(4-Methylphenyl)-2-oxo-1,2-dihydroquinoline-4-carboxylic acid (CAS 400082-48-6)
- [2-(propan-2-yl)-1,3-oxazol-4-yl]methanol (CAS 162740-03-6)
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- Methyl 3-bromo-5-fluoro-4-iodobenzoate (CAS 1160574-64-0)
- methyl 3-trifluoromethanesulfonylpropanoate (CAS 1955557-69-3)
- Des-Lys16-Tirzepatide (CAS CATO-CPTD788957)
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