2-(5-Chloro-2-hydroxybenzylidene)-1H-indene-1,3(2H)-dione CAS 25299-49-4
| CAS No. | 25299-49-4 |
| Molecular Formula | C16H9ClO3 |
| Molecular Weight | 284.69 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of 2-(5-Chloro-2-hydroxybenzylidene)-1H-indene-1,3(2H)-dione is closely related to a carboxylic acid group, a hydroxyl group, an ether linkage, chlorine substitution, a polycyclic aromatic system in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
2-(5-Chloro-2-hydroxybenzylidene)-1H-indene-1,3(2H)-dione (CAS 25299-49-4), molecular formula C16H9ClO3 and molecular weight 284.69 g/mol, is a CATO reference standard with documented purity and traceability.
Based on its molecular formula C16H9ClO3, 2-(5-Chloro-2-hydroxybenzylidene)-1H-indene-1,3(2H)-dione contains a carboxylic acid group, a hydroxyl group, an ether linkage, chlorine substitution, a polycyclic aromatic system; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 284.69 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO manufactures 2-(5-Chloro-2-hydroxybenzylidene)-1H-indene-1,3(2H)-dione under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C16H9ClO3 |
| Molecular Weight | 284.69 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 12.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1964 |
| Halogen Content | Cl-containing |
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- 1,4-Cyclohexadiene-1,2-dicarboxylicanhydride (CAS 4773-89-1)
- 2-(4-Chlorophenyl)tetrahydrofuran-3-amine (CAS 1432680-71-1)
- Levocabastine impurity 17 (CAS CATO-C4X-228917)
- N-Boc-3-bromo-D-phenylalanine (CAS 261360-77-4)
- tert-Butyl azetidin-3-yl(ethyl)carbamate hydrochloride (CAS 2044704-65-4)
- (2-Chlorophenyl)(2-methoxyphenyl)methanamine (CAS 1179084-82-2)
- 4,6-Dichloro-3-(difluoromethyl)-1H-indole (CAS 2149597-08-8)
- Tert-butylcis-3,5-diaminopiperidine-1-carboxylate (CAS 1487316-54-0)
- Heme iron polypeptide(Hematin) (CAS 14875-96-8)
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