Salbutamol Impurity 223 CAS CATO-C4X-1176223
| CAS No. | CATO-C4X-1176223 |
| Molecular Formula | C13H13ClO5 |
| Molecular Weight | 284.69 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including Salbutamol Impurity 223.
Salbutamol Impurity 223 (CAS CATO-C4X-1176223) is a certified pharmaceutical impurity reference standard with the molecular formula C13H13ClO5 and a molecular weight of 284.69 g/mol.
Owing to a carboxylic acid group, a hydroxyl group, an ether linkage, chlorine substitution, an aromatic ring system, Salbutamol Impurity 223 is typically off-white to pale yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 284.69 g/mol — guide the selection of appropriate sample preparation and analytical techniques. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
CATO manufactures Salbutamol Impurity 223 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C13H13ClO5 |
| Molecular Weight | 284.69 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 7.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Halogen Content | Cl-containing |
Related Salbutamol Standards
- Salbutamol Impurity 99 (CAS 27475-09-8)
- Salbutamol Impurity 106 (CAS CATO-C4X-1176106)
- Salbutamol Impurity 183 (CAS CATO-C4X-1176183)
- Salbutamol Impurity 220 (CAS CATO-C4X-1176220)
- Salbutamol Impurity 79 (CAS CATO-C4X-117679)
- Salbutamol Impurity 53 (CAS 54208-72-9)
- Salbutamol Impurity 60 (CAS 238762-31-7)
- Salbutamol Impurity 61 (CAS 238762-34-0)
Recommended Standards
- 2-(5-Chloro-2-hydroxybenzylidene)-1H-indene-1,3(2H)-dione (CAS 25299-49-4)
- Voriconazole Impurity 66 (CAS CATO-C4X-136666)
- 2-(4-Chlorobenzoyl)benzofuran-5-carbaldehyde (CAS 300664-78-2)
- 3-(3-Chloropropanoyl)-1-(2,3-dihydro-1,4-benzodioxin-6-yl)urea (CAS 1000930-40-4)
- Epinastine Impurity 37 (CAS 2044-27-1)
- Rivaroxaban Impurity 95 (CAS CATO-C4X-109095)
- Cefoxitin Impurity 32 (CAS 4461-29-4)
- (1S)-[1,1'-Binaphthalen]-2-ylbis(3,5-dimethylphenyl)phosphine (CAS 701935-45-7)
- Gemcitabine-13C-15N2 (CAS 1233921-74-8)
- ethyl 5-fluoro-1H-pyrrolo[2,3-b]pyridine-2-carboxylate (CAS 920978-95-6)
- 2-(Aminomethyl)-5-cyclopropoxynicotinic acid (CAS 1243371-56-3)
- N-(2-Acetyl-6-iodopyridin-4-yl)acetamide (CAS 1393566-33-0)
- 4-[(2,2,3,3-tetrafluoropropoxy)methyl]benzoic acid (CAS 444151-68-2)
- Semaglutide impurity 271 (CAS CATO-C4X-2226271)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com