N-(2-Hydroxy-4-nitrophenyl)acetamide CAS 25351-89-7
| CAS No. | 25351-89-7 |
| Molecular Formula | C8H8N2O4 |
| Molecular Weight | 196.16 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
CATO supplies N-(2-Hydroxy-4-nitrophenyl)acetamide (CAS 25351-89-7), a certified reference material (molecular formula C8H8N2O4, MW 196.16 g/mol) for analytical method development and quality control.
N-(2-Hydroxy-4-nitrophenyl)acetamide (C8H8N2O4) contains an amino-acid-derived structure, an amide group, a hydroxyl group, an ether linkage. It is notably hygroscopic, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), N-(2-Hydroxy-4-nitrophenyl)acetamide meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C8H8N2O4 |
| Molecular Weight | 196.16 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (faint amine-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 6.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1964 |
| Nitrogen Atoms | 2 |
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- 2-(2-Hydroxy-4-methoxyphenyl)-2-oxoacetic acid (CAS 120240-70-2)
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Recommended Standards
- Methyl 6-methyl-5-nitropicolinate (CAS 64215-12-9)
- N-(2-Hydroxy-5-Nitrophenyl) Acetamide (CAS 97-60-9)
- Methyl 6,7-dihydro-[1,4]dioxino[2,3-d]pyrimidine-2-carboxylate (CAS 946505-99-3)
- N-(3-Hydroxy-4-nitrophenyl)acetamide (CAS 712-34-5)
- (S)-(+)-COP-Cl Catalyst (CAS 612065-01-7)
- HO-PEG20-OH (CAS 351342-08-0)
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- N-[(Thiophen-2-yl)methyl]pyridin-2-amine (CAS 140-19-2)
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- (8-(3,4-Dimethoxyphenyl)-1,4-dioxaspiro[4.5]Decan-8-yl)methanamine (CAS 887978-91-8)
- 5-Fluoro-3-methyl-3,4-dihydro-2H-benzo[e][1,2,4]thiadiazine 1,1-dioxide (CAS 452307-81-2)
- TRAF6 Peptide trifluoroacetate salt (CAS 852805-92-6)
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