5-Fluoro-3-methyl-3,4-dihydro-2H-benzo[e][1,2,4]thiadiazine 1,1-dioxide CAS 452307-81-2
| CAS No. | 452307-81-2 |
| Molecular Formula | C8H9FN2O2S |
| Molecular Weight | 216.23 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
CATO supplies 5-Fluoro-3-methyl-3,4-dihydro-2H-benzo[e][1,2,4]thiadiazine 1,1-dioxide (CAS 452307-81-2), a certified reference material (molecular formula C8H9FN2O2S, MW 216.23 g/mol) for analytical method development and quality control.
Owing to a nitrogen-containing heterocyclic scaffold, an amide group, a sulfone group, a hydroxyl group, an ether linkage, fluorine substitution, 5-Fluoro-3-methyl-3,4-dihydro-2H-benzo[e][1,2,4]thiadiazine 1,1-dioxide is typically off-white to pale yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 216.23 g/mol — guide the selection of appropriate sample preparation and analytical techniques. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
As a certified reference material (CRM), 5-Fluoro-3-methyl-3,4-dihydro-2H-benzo[e][1,2,4]thiadiazine 1,1-dioxide meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C8H9FN2O2S |
| Molecular Weight | 216.23 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 2 |
| Sulfur Atoms | 1 |
Related Fluoro Standards
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Recommended Standards
- 6-(2-Phenylethenyl)oxane-2,4-dione (CAS 57012-11-0)
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- 6-(Allyloxy)-4-methyl-2H-chromen-2-one (CAS 90207-15-1)
- 5-(4-Ethylphenoxy)furan-2-carbaldehyde (CAS 76506-16-6)
- Methyl (E)-3-Bromo-2-methylacrylate (CAS 40053-01-8)
- 4-Carboxybutyl(triphenyl)phosphanium;bromide (CAS 17814-85-6)
- Ethyl 2-(4-(tert-butyl)cyclohexylidene)propanoate (CAS 503003-76-7)
- 2-[1-(3-Phenylpropyl)-2-piperazinyl]ethanoldihydrochloride (CAS 1273578-06-5)
- 1-((2-Hydroxyethyl)(methyl)amino)propan-2-ol (CAS 16681-45-1)
- 2-Fluoro-n-phenylbenzene-1-sulfonamide (CAS 30058-41-4)
- 2-(2-((2-Chloro-7-methylquinolin-3-yl)methylene)hydrazinyl)-3-(o-tolyl)quinazolin-4(3H)-one (CAS 327039-01-0)
- 4-(Bromomethyl)-7,8-difluoroquinolin-2(1H)-one (CAS 953070-72-9)
- 6-Amino-2-(dimethylamino)-5-propylpyrimidin-4(3h)-one (CAS 1342282-04-5)
- Tirzepatide Impurity 49 (CAS CATO-C4X-324049)
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