(5-chloro-6-fluoro-2-methyl-1H-indol-3-yl) acetate CAS 2537643-61-9
| CAS No. | 2537643-61-9 |
| Molecular Formula | C11H9ClFNO2 |
| Molecular Weight | 241.65 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 241.65 g/mol gives (5-chloro-6-fluoro-2-methyl-1H-indol-3-yl) acetate distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
(5-chloro-6-fluoro-2-methyl-1H-indol-3-yl) acetate (CAS 2537643-61-9) is a high-purity analytical reference standard with the molecular formula C11H9ClFNO2 and a molecular weight of 241.65 g/mol.
The molecular framework of (5-chloro-6-fluoro-2-methyl-1H-indol-3-yl) acetate (C11H9ClFNO2) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
As a certified reference material (CRM), (5-chloro-6-fluoro-2-methyl-1H-indol-3-yl) acetate meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C11H9ClFNO2 |
| Molecular Weight | 241.65 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 7.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2001 |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 1 |
Related chloro Standards
- 4-Chloro-1-((2-fluorophenoxy)methyl)-1,2-dihydro-3h-pyrazol-3-imine (CAS 1006435-98-8)
- 2-Chloro-5-(2-nitrophenyl)-1,3,4-thiadiazole (CAS 113111-44-7)
- Ethyl 5-chloro-7-fluoro-1H-indole-2-carboxylate (CAS 1204501-37-0)
- Ethyl 4-chloro-5-fluoro-1H-indole-2-carboxylate (CAS 153500-78-8)
- Ethyl 6-chloro-5-fluoro-1H-indole-2-carboxylate (CAS 169674-00-4)
- 5-chloro-4-(3-nitrophenyl)-1,2,3-thiadiazole (CAS 1909327-27-0)
- 2-Chloro-5-(4-nitrophenyl)-1,3,4-thiadiazole (CAS 19430-32-1)
- (3-Chloro-4-(prop-2-yn-1-ylamino)phenyl)dimethylphosphine oxide (CAS 2903923-15-7)
Recommended Standards
- (6-chloro-5-fluoro-2-methyl-1H-indol-3-yl) acetate (CAS 2627980-81-6)
- 1-[(2-chloro-4-fluorophenoxy)methyl]-1h-pyrazol-4-amine (CAS 956394-34-6)
- 2-(3-Chloro-4-fluorophenoxy)-N-(prop-2-yn-1-yl)acetamide (CAS 923243-39-4)
- 2-Chloro-5-(3-nitrophenyl)-1,3,4-thiadiazole (CAS 88541-06-4)
- 1-methyl-1H-pyrazole-4-sulfonic acid (CAS 1798770-47-4)
- Strontium zirconate (CAS 12036-39-4)
- Hexanamide, 6-azido-N-(2-chloroethyl)- (CAS 1445799-87-0)
- Caesium tris(trifluoromethanesulphonyl)methide (CAS 114395-68-5)
- 4-Methyl-1-tosylpiperidine (CAS 60212-39-7)
- 5-Chloro-2-methoxy-N-(2-methoxyethyl)-4-methylbenzenesulfonamide (CAS 1087640-21-8)
- 2,3-Dimethyl-6-(1H-pyrazol-1-yl)quinoxaline (CAS 941283-15-4)
- 5,5'-Diiodo-2,2'-dimethylbiphenyl (CAS 1392203-19-8)
- 5-Bromo-6-chloro-1H-indole-3-carboxylic acid (CAS 1467062-16-3)
- Semaglutide impurity 269 (CAS CATO-C4X-2226269)
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