4-[2-(Trifluoromethyl)phenyl]piperidine Hydrochloride CAS 255051-14-0
| CAS No. | 255051-14-0 |
| Molecular Formula | C12H14F3N |
| Molecular Weight | N/A |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
As a certified reference material (CRM), 4-[2-(Trifluoromethyl)phenyl]piperidine Hydrochloride meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
4-[2-(Trifluoromethyl)phenyl]piperidine Hydrochloride (CAS 255051-14-0) is a high-purity analytical reference standard with the molecular formula C12H14F3NHCl and a molecular weight of 265.70 g/mol.
Owing to a nitrogen-containing heterocyclic scaffold, a nitrile group, fluorine/chlorine substitution, 4-[2-(Trifluoromethyl)phenyl]piperidine Hydrochloride is typically off-white to pale yellow low-melting solid. Its solid-state physicochemical attributes — including a molecular weight of 265.70 g/mol — guide the selection of appropriate sample preparation and analytical techniques. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
Physical & Chemical Properties
| Molecular Formula | C12H14F3N HCl |
| Molecular Weight | 265.70 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 4.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 1 |
Related Trifluoromethyl Standards
- 3-(4-(Trifluoromethyl)phenyl)pyrrolidin-3-ol hydrochloride (CAS 1000198-74-2)
- 3-(4-(Trifluoromethyl)phenyl)pyrrolidine (CAS 1000198-76-4)
- (2-Methyl-4-(trifluoromethyl)thiazol-5-yl)methanol (CAS 1000339-72-9)
- methyl 3-((4-(trifluoromethyl)piperidin-1-yl)methyl)benzoate (CAS 1000339-86-5)
- methyl 4-(2-(4-(trifluoromethyl)piperidin-1-yl)ethoxy)benzoate (CAS 1000339-87-6)
- 2-(4-(trifluoromethyl)piperidin-1-yl)thiazole-5-carbaldehyde (CAS 1000339-88-7)
- 3-(2-(4-(trifluoromethyl)piperidin-1-yl)ethyl)benzaldehyde (CAS 1000339-89-8)
- 4-(2-(4-(trifluoromethyl)piperidin-1-yl)acetyl)-1H-pyrrole-2-carbaldehyde (CAS 1000339-90-1)
Recommended Standards
- 6-Bromo-3-methylbenzofuran-2-carboxylic acid (CAS 914206-99-8)
- (E)-2-acetamido-3-(3,5-difluorophenyl)acrylic acid (CAS 883035-24-3)
- Methyl 5-(methylthio)-4-phenyl-3-(1H-pyrrol-1-yl)thiophene-2-carboxylate (CAS 947598-69-8)
- N,N-Diethyl-3-hydroxy-4-iodobenzamide (CAS 911228-76-7)
- 1,3-dioxan-2-ylmethanamine (CAS 57366-83-3)
- 4-(N-Boc-N-Propylamino)-2-chlorophenylboronic acid (CAS 2377611-35-1)
- (1-ethyl-3,4-dihydro-1H-2-benzopyran-1-yl)methanamine hydrochloride (CAS 26481-46-9)
- 2-(Pyrazine-2-carboxamido)-N-(4-(trifluoromethoxy)phenyl)oxazole-4-carboxamide (CAS 1396793-35-3)
- 3-Amino-2,4,6-tribromophenol (CAS 132331-08-9)
- Tirzepatide Impurity 34 (CAS CATO-C4X-324034)
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