1-[3-(Tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl]cyclopropane-1-carboxylic acid CAS 2553271-61-5
| CAS No. | 2553271-61-5 |
| Molecular Formula | C16H21BO4 |
| Molecular Weight | 288.15 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The molecular framework of 1-[3-(Tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl]cyclopropane-1-carboxylic acid (C16H21BO4) is characterized by a carboxylic acid group, a hydroxyl group, an ether linkage, an aromatic ring system. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
1-[3-(Tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl]cyclopropane-1-carboxylic acid (CAS 2553271-61-5) is a high-purity analytical reference standard with the molecular formula C16H21BO4 and a molecular weight of 288.15 g/mol.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), 1-[3-(Tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl]cyclopropane-1-carboxylic acid meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C16H21BO4 |
| Molecular Weight | 288.15 g/mol |
| Appearance | Off-white to pale yellow crystalline powder |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 6.5 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2001 |
Related Tetramethyl Standards
- N-(5-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)pyridin-3-yl)cyclopropanecarboxamide (CAS 1201644-35-0)
- 1-(5-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)pyridin-2-yl)pyrrolidin-2-one (CAS 1201644-51-0)
- 1-(4-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)cyclopropane-1-carboxylic acid (CAS 1218790-98-7)
- N-(4-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)pyridin-2-yl)cyclopropanecarboxamide (CAS 1286230-87-2)
- 1-(6-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)pyridin-2-yl)pyrrolidin-2-one (CAS 1352645-48-7)
- 1-(4-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)pyridin-2-yl)pyrrolidin-2-one (CAS 1402240-91-8)
- 2-[5-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-indazol-1-yl]ethan-1-ol (CAS 1476076-04-6)
- 2-(6-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-benzo[d]imidazol-1-yl)ethan-1-ol (CAS 1491137-94-0)
Recommended Standards
- 1-(3,4-Dichlorophenyl)-5-imino-3-methyl-4-thioxoimidazolidin-2-one (CAS 30063-55-9)
- 2-(2,4-Dichlorophenyl)-4-methylthiazole-5-carboxylic acid (CAS 472804-18-5)
- (E)-Methyl 4-(2-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)vinyl)benzoate (CAS 223919-55-9)
- 2-(2,6-Dichlorophenyl)-4-methyl-1,3-thiazole-5-carboxylic acid (CAS 927974-31-0)
- 5-Amino-3-(3-chlorophenyl)isoxazole-4-carbonitrile (CAS 938226-53-0)
- (S)-2-(3,4-difluorophenyl)piperidine (CAS 1241683-84-0)
- 1-(4-Fluoro-3-methylphenyl)hexan-1-one (CAS 1247489-37-7)
- 6-Chloro-2-iodo-1-methyl-1H-pyrrolo[2,3-b]pyridine (CAS 1638761-52-0)
- 4-(Difluoromethyl)pyridine-3,5-diol (CAS 1805166-16-8)
- (3-(Benzyloxy)-4-bromophenyl)methanol (CAS 540779-36-0)
- 8-Ethoxy-4-methylquinolin-2-ol (CAS 88611-76-1)
- (1-((2-Chlorophenyl)sulfonyl)pyrrolidin-3-yl)methanamine (CAS 1839505-12-2)
- 9-Hydroxy-12-oxo-10-(trans)-octadecenoic Acid (CAS 28979-47-7)
- Semaglutide impurity 290 (CAS CATO-C4X-2226290)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com