2-(2,4-Dichlorophenyl)-4-methylthiazole-5-carboxylic acid CAS 472804-18-5
| CAS No. | 472804-18-5 |
| Molecular Formula | C11H7Cl2NO2S |
| Molecular Weight | 288.15 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
2-(2,4-Dichlorophenyl)-4-methylthiazole-5-carboxylic acid (CAS 472804-18-5) is a high-purity analytical reference standard with the molecular formula C11H7Cl2NO2S and a molecular weight of 288.15 g/mol.
The molecular framework of 2-(2,4-Dichlorophenyl)-4-methylthiazole-5-carboxylic acid (C11H7Cl2NO2S) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a sulfone group, a hydroxyl group, an ether linkage, chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
As a certified reference material (CRM), 2-(2,4-Dichlorophenyl)-4-methylthiazole-5-carboxylic acid meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C11H7Cl2NO2S |
| Molecular Weight | 288.15 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 8.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 1 |
| Sulfur Atoms | 1 |
Related Dichlorophenyl Standards
- 2-(2-(2,6-Dichlorophenyl)thiazol-5-yl)acetic acid (CAS 1010872-22-6)
- 2-[2-(2,3-dichlorophenyl)-1,3-thiazol-4-yl]acetic acid (CAS 1094293-77-2)
- 2-(2,3-Dichlorophenyl)-4-methyl-1,3-thiazole-5-carboxylic acid (CAS 1094457-01-8)
- Methyl 2-(3,5-dichlorophenyl)thiazole-4-carboxylate (CAS 1548643-66-8)
- 4-((2,6-Dichlorophenyl)amino)thiophene-3-carboxylic acid (CAS 16562-98-4)
- 2-(2,3-Dichlorophenyl)thiazole-4-carbohydrazide (CAS 175276-87-6)
- 2-[2-(2,4-dichlorophenyl)-1,3-thiazol-4-yl]acetic acid (CAS 17969-29-8)
- N-(2,4-Dichlorophenyl)-4-methyl-1,2,3-thiadiazole-5-carboxamide (CAS 183300-50-7)
Recommended Standards
- 1-[3-(Tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl]cyclopropane-1-carboxylic acid (CAS 2553271-61-5)
- 2-(2,6-Dichlorophenyl)-4-methyl-1,3-thiazole-5-carboxylic acid (CAS 927974-31-0)
- 1-(3,4-Dichlorophenyl)-5-imino-3-methyl-4-thioxoimidazolidin-2-one (CAS 30063-55-9)
- 2-(3,4-Dichlorophenyl)-4-methylthiazole-5-carboxylic acid (CAS 343322-58-7)
- Morpholine-2-carbonitrile 4-methylbenzenesulfonate (CAS 1820717-22-3)
- 2-[(4-chlorophenyl)amino]-2-methylpropanoic acid (CAS 17413-86-4)
- 1-tert-Butyl 2-methyl (2R,4S)-4-methylpyrrolidine-1,2-dicarboxylate (CAS 879374-49-9)
- 2-Pivaloylcycloheptan-1-one (CAS 275383-53-4)
- Methyl 2-methoxy-6-(trifluoromethyl)nicotinate (CAS 917396-36-2)
- 3-bromo-[2,3'-bifuran]-2'-carboxylic acid (CAS 2025822-81-3)
- 2-(4-Chlorophenyl)-4-(4-(trifluoromethyl)phenyl)thiomorpholine-3,5-dione 1-oxide (CAS 252058-94-9)
- 1-Cbz-N,N-dimethylpiperidine-3-carboxamide (CAS 2006277-71-8)
- Methyl 6-(2-(1H-tetrazol-5-yl)phenoxy)nicotinate (CAS 1211770-65-8)
- [α-Glu](Sidechain trans-position)-Liraglutide (CAS CATO-C4X-199240)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com