(5S)-3,3-difluoro-5-(hydroxymethyl)pyrrolidin-2-one CAS 255903-84-5
| CAS No. | 255903-84-5 |
| Molecular Formula | C5H7F2NO2 |
| Molecular Weight | 151.11 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
CATO manufactures (5S)-3,3-difluoro-5-(hydroxymethyl)pyrrolidin-2-one under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
(5S)-3,3-difluoro-5-(hydroxymethyl)pyrrolidin-2-one (CAS 255903-84-5) is a high-purity analytical reference standard with the molecular formula C5H7F2NO2 and a molecular weight of 151.11 g/mol.
The molecular framework of (5S)-3,3-difluoro-5-(hydroxymethyl)pyrrolidin-2-one (C5H7F2NO2) is characterized by an amide group, a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C5H7F2NO2 |
| Molecular Weight | 151.11 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 2.0 |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 1 |
Related S Standards
- 3,3-Difluoro-5-hydroxypiperidin-2-one (CAS 1256080-98-4)
- (R)-3,3-Difluoro-5-(hydroxymethyl)pyrrolidin-2-one (CAS 1544279-19-7)
- 3,4-difluoro-1h-pyrrole-2-carboxylic acid (CAS 160561-81-9)
- 2,3-difluoro-4-methoxy-pyridine (CAS 1227578-88-2)
- 3,3-Difluoro-4-methoxypiperidine (CAS 1373609-11-0)
- [(2R)-4,4-difluoro-1-methylpyrrolidin-2-yl]methanol (CAS 1408002-86-7)
- (S)-4,4-Difluoro-1-methylpyrrolidine-2-methanol (CAS 1408057-44-2)
- 3,3-Difluoro-1-methylpiperidin-4-ol (CAS 1504212-61-6)
Recommended Standards
- (2S)-4,4-difluoropyrrolidine-2-carboxylic acid (CAS 52683-81-5)
- tert-Butyl(methyl)selane (CAS 37773-03-8)
- 4-(1,1-Difluoroethyl)-3-hydroxyazetidin-2-one (CAS 1824387-82-7)
- L-Glutamine-13C5 (CAS 184161-19-1)
- 4-Isobutoxy-2,6-dimethylbenzaldehyde (CAS 1443312-84-2)
- 3-Methyl-2,3,4,9-tetrahydro-1H-carbazole (CAS 6933-54-6)
- 9-(Benzyloxy)-9H-purin-6-amine (CAS 61193-37-1)
- 2,4-Dimethoxy-N-(3-(3-methylpentan-3-yl)isoxazol-5-yl)benzamide (CAS 189038-97-9)
- N-(2-Chloroethyl)cyclopropanamine (CAS 61272-38-6)
- Pcb No. 179 (CAS 52663-64-6)
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Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com