1-(Chloromethyl)-4-(diethoxyphosphorylmethyl)benzene CAS 25596-72-9
| CAS No. | 25596-72-9 |
| Molecular Formula | C12H18ClO3P |
| Molecular Weight | 276.70 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 1-(Chloromethyl)-4-(diethoxyphosphorylmethyl)benzene.
1-(Chloromethyl)-4-(diethoxyphosphorylmethyl)benzene (CAS 25596-72-9) is a high-purity analytical reference standard with the molecular formula C12H18ClO3P and a molecular weight of 276.70 g/mol.
Structurally, 1-(Chloromethyl)-4-(diethoxyphosphorylmethyl)benzene (C12H18ClO3P) contains a phosphonate group, a carboxylic acid group, a hydroxyl group, an ether linkage, chlorine substitution. The molecule exhibits a degree of unsaturation (DBE) of 3.5, corresponding to approximately 3 ring(s) or double-bond equivalent(s). With a molecular weight of 276.70 g/mol, it falls into the medium-molecular-weight range. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C12H18ClO3P |
| Molecular Weight | 276.70 g/mol |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 3.5 |
| UV Absorption | UV-absorbing |
| CAS Registry Year (est.) | 1964 |
| Halogen Content | Cl-containing |
Related Chloromethyl Standards
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Recommended Standards
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