2-(Chloromethyl)-6-phenyl-3h,4h-thieno[2,3-d]pyrimidin-4-one CAS 852218-16-7
| CAS No. | 852218-16-7 |
| Molecular Formula | C13H9ClN2OS |
| Molecular Weight | 276.74 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
2-(Chloromethyl)-6-phenyl-3h,4h-thieno[2,3-d]pyrimidin-4-one (CAS 852218-16-7) is a high-purity analytical reference standard with the molecular formula C13H9ClN2OS and a molecular weight of 276.74 g/mol.
2-(Chloromethyl)-6-phenyl-3h,4h-thieno[2,3-d]pyrimidin-4-one (C13H9ClN2OS) contains a nitrogen-containing heterocyclic scaffold, an amide group, sulfur-containing functionality, a hydroxyl group, an ether linkage, chlorine substitution. Halogen substitution raises its density and boiling point, its high carbon-to-hydrogen ratio confers good lipid solubility; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C13H9ClN2OS |
| Molecular Weight | 276.74 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 10.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1987 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 2 |
| Sulfur Atoms | 1 |
Related Chloromethyl Standards
- 2-(Chloromethyl)-5-phenylthieno[2,3-d]pyrimidin-4-ol (CAS 89567-07-7)
- 7-(Chloromethyl)-3-phenyl-5H-[1,3]thiazolo[3,2-a]pyrimidin-5-one (CAS 85811-56-9)
- 4-(Chloromethyl)-1-cyclohexyl-2-(trifluoromethyl)benzene (CAS 957205-24-2)
- Ethyl 4-(chloromethyl)-2-phenylpyrimidine-5-carboxylate (CAS 1440526-40-8)
- 7-(Chloromethyl)tetraphene (CAS 6325-54-8)
- 5-(Chloromethyl)-1-cyclohexyl-2-methanesulfonyl-1h-imidazole (CAS 1221341-09-8)
- Ethyl 4-(chloromethyl)-2-(isobutylimino)-2,3-dihydrothiazole-5-carboxylate (CAS 937597-83-6)
- 1-(Chloromethyl)-4-(diethoxyphosphorylmethyl)benzene (CAS 25596-72-9)
Recommended Standards
- 2-[(4-Chlorophenyl)sulfanyl]-4-methoxypyridine-3-carbonitrile (CAS 338773-69-6)
- 2-(Benzylthio)-5-chloro-[1,2,4]triazolo[1,5-a]pyrimidine (CAS 98968-28-6)
- 2-Benzylthio-6-chloropurine (CAS 51998-91-5)
- 1-(4-Chlorophenyl)-4-(methylthio)-1H-pyrazolo[3,4-d]pyrimidine (CAS 893912-39-5)
- 1,2-thiazol-4-amine dihydrochloride (CAS 1955519-82-0)
- 10-(Pyridin-3-yl)-2,3,6,7-tetrahydro-1H-pyrano[2,3-f]pyrido[3,2,1-ij]quinolin-11(5H)-one (CAS 87349-92-6)
- (2e)-3-[1-benzyl-3-(4-ethylphenyl)-1h-pyrazol-4-yl]prop-2-enoic acid (CAS 956747-08-3)
- Ambroxol Impurity 52 (CAS 946122-05-0)
- 4,4-Dimethyl-2-(2,4,5-trifluoro-3-methylphenyl)-4,5-dihydrooxazole (CAS 132630-83-2)
- (2R,4S)-rel-4-Methyl-1,2-piperidinedicarboxylic Acid 1-(1,1-Dimethylethyl) Ester (CAS 187752-72-3)
- 1-(3-Fluoro-4-methylphenyl)-3-(1-methyl-1H-indol-3-yl)urea (CAS 941879-45-4)
- Pranoprofen Impurity 14 (CAS CATO-C4X-181114)
- 5-Isopropyl-3-phenyl-7-(piperidin-1-yl)pyrazolo[1,5-a]pyrimidine (CAS 890628-46-3)
- Semaglutide impurity 45 (CAS CATO-C4X-222645)
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