Ritonavir EP Impurity L CAS 256328-82-2
| CAS No. | 256328-82-2 |
| Molecular Formula | C33H43N5O4S |
| Molecular Weight | 605.79 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Ritonavir EP Impurity L (CAS 256328-82-2) is a certified pharmaceutical impurity reference standard with the molecular formula C33H43N5O4S and a molecular weight of 605.79 g/mol.
Owing to a nitrogen-containing heterocyclic scaffold, an amide group, a sulfone group, a hydroxyl group, an ether linkage, Ritonavir EP Impurity L is typically pale yellow to yellow amorphous powder. Its solid-state physicochemical attributes — including a molecular weight of 605.79 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
Physical & Chemical Properties
| Molecular Formula | C33H43N5O4S |
| Molecular Weight | 605.79 g/mol |
| Purity | >95% |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 15.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Nitrogen Atoms | 5 |
| Sulfur Atoms | 1 |
Related Ritonavir Standards
- Ritonavir Impurity A RRT 5.78 (CAS 959351-57-6)
- Ritonavir Impurity 45 (CAS 1010809-50-3)
- Ritonavir EP Impurity H (CAS 1010809-43-4)
- Ritonavir Impurity 46 (CAS 1010809-54-7)
- Ritonavir EP Impurity D (CAS 144142-33-6)
- Ritonavir Impurity 61 (CAS CATO-C4X-175161)
- Ritonavir EP Impurity F (CAS 1010809-61-6)
- Ritonavir EP Impurity J (CAS 162849-95-8)
Recommended Standards
- [S(R)]-N-[(1S)-2-(Diphenylphosphino)-1-[2-(dicyclohexylphosphanyl)phenyl]ethyl]-2-methyl-2-propanesulfinamide (CAS 2565792-85-8)
- Trt-Cys(Trt)-OH (CAS 27686-50-6)
- Phenol, 2-[4,6-bis([1,1'-biphenyl]-4-yl)-1,3,5-triazin-2-yl]-5-[(2-ethylhexyl)oxy]- (CAS 204583-39-1)
- Fluphenazine Decanoate EP Impurity F (CAS 13220-06-9)
- Eravacycline Impurity 6(TP-5576） (CAS CATO-C4X-29386)
- Larotrectinib Impurity 15 (CAS CATO-C4X-238015)
- Trifarotene impurity 25 (CAS CATO-C4X-313225)
- 4,6-Diamino-2-iodonicotinonitrile (CAS 70172-54-2)
- tert-butyl N-[(5,6-dimethylpiperidin-2-yl)methyl]carbamate (CAS 1934550-27-2)
- 3-[(3-Amino-1H-1,2,4-triazol-5-yl)sulfanyl]-5-(trifluoromethyl)pyridine-2-carbonitrile (CAS 338968-23-3)
- 2-(Propylthio)-1-(o-tolyl)ethan-1-one (CAS 1157366-88-5)
- 3-(3-Chloro-5-fluorophenyl)-1-cyclohexylpropan-1-one (CAS 898751-73-0)
- 2,2-Diethoxy-4-methyl-5-methylene-2,5-dihydrofuran (CAS 87841-02-9)
- Endo-Pro36-Tirzepatide (CAS CATO-CPTD788688)
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