Baloxavir Marboxil Impurity 159 CAS 2563540-50-9
| CAS No. | 2563540-50-9 |
| Molecular Formula | C14H11FO2S |
| Molecular Weight | 262.30 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including Baloxavir Marboxil Impurity 159.
Baloxavir Marboxil Impurity 159 (CAS 2563540-50-9) is a certified pharmaceutical impurity reference standard with the molecular formula C14H11FO2S and a molecular weight of 262.30 g/mol.
Owing to a sulfone group, a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine substitution, a polycyclic aromatic system, Baloxavir Marboxil Impurity 159 is typically pale yellow to yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 262.30 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C14H11FO2S |
| Molecular Weight | 262.30 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 9.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2001 |
| Halogen Content | F-containing |
| Sulfur Atoms | 1 |
Related Baloxavir Standards
- Baloxavir Impurity 137 (CAS CATO-C4X-2108137)
- Baloxavir Impurity 139 (CAS CATO-C4X-2108139)
- Baloxavir Impurity 143 (CAS CATO-C4X-2108143)
- Baloxavir Marboxil Impurity 199 (CAS CATO-C4X-2108199)
- Baloxavir Marboxil Impurity 200 (CAS CATO-C4X-2108200)
- Baloxavir Marboxil Impurity 205 (CAS CATO-C4X-2108205)
- Baloxavir Marboxil Impurity 222 (CAS CATO-C4X-2108222)
- Baloxavir Impurity 34 (CAS 2136287-66-4)
Recommended Standards
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- Serotonin Impurity 9 (CAS CATO-C4X-25349)
- Mizolastine Impurity 5 (CAS 130212-30-5)
- Topiramate Impurity 23 (CAS 18549-40-1)
- Tirofiban Impurity 117 (CAS CATO-C4X-1254117)
- ethyl trans-3-fluoro-3-(iodomethyl)cyclobutanecarboxylate (CAS 2378501-51-8)
- Exendin-4 (3-39) (CAS 196109-31-6)
- 0234AD 1185295-17-3 3-(Methyl-pyridin-3-ylmethyl-amino)-propionic acid dihydrochloride C10H16Cl2N2O2 (CAS 1185295-17-3)
- Potassium 2-amino-4-(trifluoromethyl)benzenesulfonate (CAS 474650-43-6)
- 2-Amino-4-(4-chlorophenyl)-6-ethyl-5-methylnicotinonitrile (CAS 338794-05-1)
- Cefaclor (CAS 53994-73-3)
- Heme iron polypeptide(Hematin) (CAS 14875-96-8)
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