Baloxavir Marboxil Impurity 222 CAS CATO-C4X-2108222
| CAS No. | CATO-C4X-2108222 |
| Molecular Formula | C14H8F2OS |
| Molecular Weight | 262.27 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
As a process- or degradation-related impurity, Baloxavir Marboxil Impurity 222 (CAS CATO-C4X-2108222, C14H8F2OS) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
Baloxavir Marboxil Impurity 222 (C14H8F2OS) contains sulfur-containing functionality, a hydroxyl group, an ether linkage, fluorine substitution, a polycyclic aromatic system. Halogen substitution raises its density and boiling point, its high carbon-to-hydrogen ratio confers good lipid solubility; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
As a certified reference material (CRM), Baloxavir Marboxil Impurity 222 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C14H8F2OS |
| Molecular Weight | 262.27 g/mol |
| Purity | ≥95% |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 10.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Halogen Content | F-containing |
| Sulfur Atoms | 1 |
Related Baloxavir Standards
- Baloxavir Impurity 143 (CAS CATO-C4X-2108143)
- Baloxavir Marboxil Impurity 199 (CAS CATO-C4X-2108199)
- Baloxavir Marboxil Impurity 200 (CAS CATO-C4X-2108200)
- Baloxavir Marboxil Impurity 205 (CAS CATO-C4X-2108205)
- Baloxavir Impurity 34 (CAS 2136287-66-4)
- Baloxavir Impurity 137 (CAS CATO-C4X-2108137)
- Baloxavir Impurity 139 (CAS CATO-C4X-2108139)
- Baloxavir Marboxil Impurity 159 (CAS 2563540-50-9)
Recommended Standards
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- Cyclophosphamide Impurity 21 (CAS 2517939-95-4)
- Cariprazine Impurity 67 (CAS CATO-C4X-240867)
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