Luliconazole Impurity 3 CAS 256424-63-2
| CAS No. | 256424-63-2 |
| Molecular Formula | C14H9Cl2N3S2 |
| Molecular Weight | 354.28 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Owing to a nitrogen-containing heterocyclic scaffold, a nitrile group, sulfur-containing functionality, chlorine substitution, Luliconazole Impurity 3 is typically pale yellow to yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 354.28 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
As a process- or degradation-related impurity, Luliconazole Impurity 3 (CAS 256424-63-2, C14H9Cl2N3S2) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
As a certified reference material (CRM), Luliconazole Impurity 3 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C14H9Cl2N3S2 |
| Molecular Weight | 354.28 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 11.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 3 |
| Sulfur Atoms | 2 |
Related Luliconazole Standards
- Luliconazole (CAS 187164-19-8)
- Luliconazole Impurity 15 (CAS CATO-C4X-285315)
- Luliconazole Impurity 16 (CAS CATO-C4X-285316)
- Luliconazole Impurity 2 (CAS 1240249-76-6)
- Rac-Luliconazole-Z-Isomer (CAS 101529-76-4)
- Rac-Luliconazole-E-Isomer (CAS 101530-21-6)
- Luliconazole Impurity 7 (CAS 2522922-36-5)
- Luliconazole Impurity 11 (CAS CATO-C4X-285311)
Recommended Standards
- 3-[5-(1,5-dimethyl-1h-pyrazol-4-yl)-7-(trifluoromethyl)-[1,2,4]triazolo[1,5-a]pyrimidin-2-yl]propanoic acid (CAS 1174878-30-8)
- tert-Butyl 4-(4-bromobenzyl)piperidine-1-carboxylate (CAS 336182-21-9)
- 3-(5-(1-Ethyl-1h-pyrazol-4-yl)-7-(trifluoromethyl)-[1,2,4]triazolo[1,5-a]pyrimidin-2-yl)propanoic acid (CAS 1174881-80-1)
- 2-[2-bromo-4-(propan-2-yl)phenoxy]-1-(4-methylpiperidin-1-yl)ethan-1-one (CAS 768373-76-8)
- Amisulpride Impurity 62 (CAS CATO-C4X-104562)
- Ilaprazole Impurity 19 (CAS 1360824-56-1)
- Ala-Gly-Cys-Lys-Ala(CN)-Phe-Phe-Trp-Lys-Thr-Phe-Thr-Ser-Cys-OH(disulfide bond) (CAS CATO-CPTD788765)
- 1-Methyl-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrrolo[2,3-b]pyridin-2(3H)-one (CAS 1487357-03-8)
- 2,2,3,3,3-Pentafluoro-1-(thiophen-2-yl)propan-1-one (CAS 7686-81-9)
- 2-(1,3-Dioxo-2-phenyl-2,3-dihydro-1H-inden-2-yl)acetic acid (CAS 7443-02-9)
- 6-Methoxy-2-(piperazin-1-ylmethyl)-1H-benzo[d]imidazole dihydrochloride (CAS 1177360-44-9)
- Ca (CAS CATO-CCRM106015)
- 2-(Diphenylphosphino)-N-[(9S)-6′-methoxycinchonan-9-yl]benzamide (CAS 2271134-66-6)
- Mast Cell Degranulating Peptide (CAS 83856-13-7)
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