tert-Butyl (S)-3-amino-3-(trifluoromethyl)pyrrolidine-1-carboxylate CAS 2566267-75-0
| CAS No. | 2566267-75-0 |
| Molecular Formula | C10H17F3N2O2 |
| Molecular Weight | 254.25 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
tert-Butyl (S)-3-amino-3-(trifluoromethyl)pyrrolidine-1-carboxylate (CAS 2566267-75-0), molecular formula C10H17F3N2O2 and molecular weight 254.25 g/mol, is a CATO reference standard with documented purity and traceability.
Owing to an amide group, a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine substitution, tert-Butyl (S)-3-amino-3-(trifluoromethyl)pyrrolidine-1-carboxylate is typically white to off-white crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 254.25 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
Physical & Chemical Properties
| Molecular Formula | C10H17F3N2O2 |
| Molecular Weight | 254.25 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 2.0 |
| CAS Registry Year (est.) | 2001 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 2 |
Recommended Standards
- Tert-butyl (1-(2,2,2-trifluoroethyl)azetidin-3-yl)carbamate (CAS 2231674-11-4)
- Tert-butyl 3-(1-amino-2,2,2-trifluoroethyl)azetidine-1-carboxylate (CAS 2167084-96-8)
- Tert-butyl ((3S,4S)-4-(trifluoromethyl)pyrrolidin-3-yl)carbamate (CAS 2306245-97-4)
- tert-butyl 3-(trifluoromethyl)piperazine-1-carboxylate (CAS 886779-69-7)
- 4,5-Dichloro-6-methylpyridine-3-carboxylic acid (CAS 1394689-91-8)
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