Cinacalcet Impurity 26 CAS 1201-74-7
| CAS No. | 1201-74-7 |
| Molecular Formula | C12H13N |
| Molecular Weight | 171.24 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 171.24 g/mol gives Cinacalcet Impurity 26 distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
As a process- or degradation-related impurity, Cinacalcet Impurity 26 (CAS 1201-74-7, C12H13N) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
The molecular framework of Cinacalcet Impurity 26 (C12H13N) is characterized by a nitrogen-containing heterocyclic scaffold, a nitrile group. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C12H13N |
| Molecular Weight | 171.24 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate |
| Stability | Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 7.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1957 |
| Nitrogen Atoms | 1 |
Related Cinacalcet Standards
- Cinacalcet Impurity 26 (CAS 42882-31-5)
- Cinacalcet Impurity 42 (CAS 3906-16-9)
- Cinacalcet Impurity 23 (CAS 3886-70-2)
- Cinacalcet Impurity 48 (CAS 10420-89-0)
- Cinacalcet Impurity 4 (CAS 7228-47-9)
- Cinacalcet Impurity 8 (CAS 1517-72-2)
- Cinacalcet Impurity 50 (CAS 941-98-0)
- Cinacalcet Impurity 29 (CAS 1020414-30-5)
Recommended Standards
- Carfilzomib Impurity 8 (CAS CATO-C4X-10228)
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- Terbinafine EP Impurity A (CAS 14489-75-9)
- Pemafibrate Impurity 41 (CAS CATO-C4X-290341)
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