N-(4-fluorophenyl)-2-((4-oxo-3-phenyl-3,4-dihydroquinazolin-2-yl)thio)acetamide CAS 256955-31-4
| CAS No. | 256955-31-4 |
| Molecular Formula | C22H16FN3O2S |
| Molecular Weight | 405.44 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including N-(4-fluorophenyl)-2-((4-oxo-3-phenyl-3,4-dihydroquinazolin-2-yl)thio)acetamide.
N-(4-fluorophenyl)-2-((4-oxo-3-phenyl-3,4-dihydroquinazolin-2-yl)thio)acetamide (CAS 256955-31-4), molecular formula C22H16FN3O2S and molecular weight 405.44 g/mol, is a CATO reference standard with documented purity and traceability.
Structurally, N-(4-fluorophenyl)-2-((4-oxo-3-phenyl-3,4-dihydroquinazolin-2-yl)thio)acetamide (C22H16FN3O2S) contains a steroid core, an amide group, a sulfone group, a hydroxyl group, an ether linkage, fluorine substitution. The molecule exhibits a degree of unsaturation (DBE) of 16.0, corresponding to approximately 16 ring(s) or double-bond equivalent(s). With a molecular weight of 405.44 g/mol, it falls into the moderately-high-molecular-weight range. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), N-(4-fluorophenyl)-2-((4-oxo-3-phenyl-3,4-dihydroquinazolin-2-yl)thio)acetamide meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C22H16FN3O2S |
| Molecular Weight | 405.44 g/mol |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 16.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 3 |
| Sulfur Atoms | 1 |
Related N Standards
- 2-(4-(4-Fluorophenyl)piperazin-1-yl)-N-(4-phenoxyphenyl)acetamide (CAS 524063-21-6)
- N-(4-(((4-fluorophenyl)thio)methyl)phenyl)-3-(trifluoromethyl)benzamide (CAS 338398-70-2)
- 3-((4-Fluorophenyl)sulfonyl)-2-hydroxy-2-methyl-N-(3-(trifluoromethyl)phenyl)propanamide (CAS 338424-61-6)
- (5-((4-Fluorophenyl)sulfonyl)-1-methyl-3-(trifluoromethyl)-1H-pyrazol-4-yl)methyl cyclopropanecarboxylate (CAS 956193-71-8)
- (S)-4-(5-(4-Fluorophenyl)-2-(methylthio)-1H-imidazol-4-yl)-N-(1-phenylethyl)pyridin-2-amine (CAS 581098-48-8)
- 1-(4-(4-Fluorophenyl)piperazin-1-yl)-2-(2-(trifluoromethyl)-1H-benzo[d]imidazol-1-yl)ethan-1-one (CAS 383148-66-1)
- 2-(2-Fluorophenyl)-5-[3-(4-fluorophenyl)-2,1-benzoxazol-5-yl]-5-methyl-1,2,4-triazolidin-3-one (CAS 321433-43-6)
- 2-(3-Fluorophenyl)-5-[3-(4-fluorophenyl)-2,1-benzoxazol-5-yl]-5-methyl-1,2,4-triazolidin-3-one (CAS 321433-44-7)
Recommended Standards
- Methyl (2S,4R)-4-benzamido-1-((tert-butoxycarbonyl)glycyl)pyrrolidine-2-carboxylate (CAS 943134-40-5)
- Naphthalen-1-yl 2-(4-methoxyphenyl)quinoline-4-carboxylate (CAS 332381-73-4)
- Ethyl 3-[(1,3-benzodioxol-5-ylamino)sulfonyl]benzo[b]thiophene-2-carboxylate (CAS 941919-06-8)
- Naphthalen-2-yl 2-(4-methoxyphenyl)quinoline-4-carboxylate (CAS 332381-51-8)
- 2-Chloro-N-ethyl-N-methylethanamine (CAS 54153-16-1)
- 1-2-3-Tri-O-benzyl-4-6-O-benzylidene-α-D-mannopyranose (CAS 57783-75-2)
- 3-(4-Chlorophenyl)-3-methoxypropiophenone (CAS 898787-64-9)
- 3-Methyl-N-(pyridin-3-ylmethyl)but-2-enamide (CAS 1197803-06-7)
- 3-Methyl-1H-isoindole-1-carboxylic acid (CAS 37812-42-3)
- 4-(piperidin-1-yl-ethoxyÂ)-benzÂoylÂchloride hydrochloride (CAS 84449-81-0)
- Phorbol 13-myristate (CAS 115905-51-6)
- 1-Benzyl-3-piperidin-4-ylimidazolidin-2-one (CAS 72338-90-0)
- 1902AB 247170-27-0 3-Fluoro-4-(trifluoromethyl)benzamide C8H5F4NO (CAS 247170-27-0)
- (Glu1)-Fibrinopeptide B (human) (CAS 103213-49-6)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com