1-(4-(4-Fluorophenyl)piperazin-1-yl)-2-(2-(trifluoromethyl)-1H-benzo[d]imidazol-1-yl)ethan-1-one CAS 383148-66-1
| CAS No. | 383148-66-1 |
| Molecular Formula | C20H18F4N4O |
| Molecular Weight | 406.38 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of 1-(4-(4-Fluorophenyl)piperazin-1-yl)-2-(2-(trifluoromethyl)-1H-benzo[d]imidazol-1-yl)ethan-1-one is closely related to a steroid core, an amide group, a hydroxyl group, an ether linkage, fluorine substitution in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
CATO supplies 1-(4-(4-Fluorophenyl)piperazin-1-yl)-2-(2-(trifluoromethyl)-1H-benzo[d]imidazol-1-yl)ethan-1-one (CAS 383148-66-1), a certified reference material (molecular formula C20H18F4N4O, MW 406.38 g/mol) for analytical method development and quality control.
The molecular framework of 1-(4-(4-Fluorophenyl)piperazin-1-yl)-2-(2-(trifluoromethyl)-1H-benzo[d]imidazol-1-yl)ethan-1-one (C20H18F4N4O) is characterized by a steroid core, an amide group, a hydroxyl group, an ether linkage, fluorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C20H18F4N4O |
| Molecular Weight | 406.38 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at room temperature, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 12.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 4 |
Related Fluorophenyl Standards
- 2-(2-Fluorophenyl)-5-[3-(4-fluorophenyl)-2,1-benzoxazol-5-yl]-5-methyl-1,2,4-triazolidin-3-one (CAS 321433-43-6)
- 2-(3-Fluorophenyl)-5-[3-(4-fluorophenyl)-2,1-benzoxazol-5-yl]-5-methyl-1,2,4-triazolidin-3-one (CAS 321433-44-7)
- (5-((4-Fluorophenyl)sulfonyl)-1-methyl-3-(trifluoromethyl)-1H-pyrazol-4-yl)methyl cyclopropanecarboxylate (CAS 956193-71-8)
- 1-Benzyl-3-(2-((3-(4-fluorophenyl)-[1,2,4]triazolo[4,3-b]pyridazin-6-yl)oxy)ethyl)urea (CAS 1020976-71-9)
- Ethyl 1-(5-((3-fluorophenyl)carbamoyl)-1,3,4-thiadiazole-2-carbonyl)piperidine-4-carboxylate (CAS 1142210-66-9)
- N1-((1-((4-Fluorophenyl)carbamoyl)piperidin-4-yl)methyl)-N2-((tetrahydrofuran-2-yl)methyl)oxalamide (CAS 1286706-41-9)
- 7-(4-Fluorophenyl)-2-(4-phenylpiperazin-1-yl)thieno[3,2-d]pyrimidin-4(1H)-one (CAS 1242931-70-9)
- 3-(4-Fluorophenyl)-5-(morpholin-4-yl)-7-(phenylamino)-1,4-thiazepine-6-carbonitrile (CAS 338401-15-3)
Recommended Standards
- (S)-Naproxen Iso-acyl-β-D-glucuronide (CAS 219476-92-3)
- (S)-Naproxen Acyl-beta-D-glucuronide (CAS 41945-43-1)
- (4E)-4-[(2H-1,3-Benzodioxol-5-yl)methylidene]-2-({[3-(trifluoromethyl)phenyl]methyl}sulfanyl)-4,5-dihydro-1H-imidazol-5-one (CAS 860612-11-9)
- 3-Chloro-2-(3,5-dibromo-1H-1,2,4-triazol-1-yl)-5-(trifluoromethyl)pyridine (CAS 320424-27-9)
- 3-(4-Methylbenzo[d]thiazol-2-yl)-2-phenylquinazolin-4(3H)-one (CAS 918154-65-1)
- N-methylazetidin-3-amine dihydrochloride (CAS 136293-86-2)
- 4-Methoxy-2-(piperidin-4-yloxy)pyrimidine hydrochloride (CAS 1713162-80-1)
- 4-AMINO-2-(3-METHOXYPHENYL)-6,7-DIHYDRO-5H-CYCLOPENTA[D]PYRIMIDINE (CAS 1275675-85-8)
- 1-(5-Chloro-3-fluoropyridin-2-yl)ethan-1-amine (CAS 1384264-43-0)
- 3-Methyl-1-[4-(trifluoromethoxy)phenyl]-1h-pyrazol-5-amine (CAS 497141-59-0)
- n-Methylcyclopentanesulfonamide (CAS 401583-58-2)
- H-Arg-Trp-NH2·2 HCl (CAS 281659-95-8)
- 7-Fluoro-5-iodo-1H-indazole (CAS 1260381-29-0)
- Crustacean Cardioactive Peptide (CAS 107090-96-0)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com