Quetiapine Impurity 81 CAS 257-15-8

Description

Compared with other compounds in its class, the molecular weight of 211.28 g/mol gives Quetiapine Impurity 81 distinctive chromatographic separation conditions and mass-spectrometry parameter settings.

Quetiapine Impurity 81 (CAS 257-15-8) is a certified pharmaceutical impurity reference standard with the molecular formula C13H9NS and a molecular weight of 211.28 g/mol.

The molecular framework of Quetiapine Impurity 81 (C13H9NS) is characterized by a nitrogen-containing heterocyclic scaffold, a nitrile group, sulfur-containing functionality. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.

This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.

CATO manufactures Quetiapine Impurity 81 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.

Physical & Chemical Properties

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